C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ephrin A1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027954 Efna1 10090 - 3:89271733-89281142 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029566 Efna1-001 89271733-89279645 protein_coding
  ENSMUST00000118587 Efna1-002 89271736-89281142 protein_coding
  ENSMUST00000118860 Efna1-003 89271740-89279641 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029566ENSMUST00000118860
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029566 20.890±3.98 10.643±4.40 17.934±1.99 3.062±1.21 16.144±3.39 78.216±9.42 15.002±2.10 24.493±2.72 23.053±15.57 67.170±7.39 4.639±0.91 20.040±6.94 31.584±11.66 0.656±0.16
ENSMUST00000118860 N/A 3.687±0.97 N/A 0.929±0.00 N/A N/A N/A N/A N/A N/A N/A 1.298±0.00 N/A 0.065±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000187 IDA activation of MAPK activity
GO:0001525 IEA angiogenesis
GO:0003180 IMP aortic valve morphogenesis
GO:0003183 IMP mitral valve morphogenesis
GO:0003199 IMP endocardial cushion to mesenchymal transition involved in heart valve formation
GO:0005515 IPI protein binding
GO:0007411 IBA axon guidance
GO:0010719 IMP negative regulation of epithelial to mesenchymal transition
GO:0014028 IGI notochord formation
GO:0016020 IEA membrane
GO:0016477 IEA cell migration
GO:0030182 IDA neuron differentiation
GO:0033628 IEA regulation of cell adhesion mediated by integrin
GO:0034446 IEA substrate adhesion-dependent cell spreading
GO:0043535 IDA regulation of blood vessel endothelial cell migration
GO:0045765 IDA regulation of angiogenesis
GO:0046658 IDA anchored component of plasma membrane
GO:0046875 IBA ephrin receptor binding
GO:0048013 IDA ephrin receptor signaling pathway
GO:0050730 IDA regulation of peptidyl-tyrosine phosphorylation
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050770 IDA regulation of axonogenesis
GO:0061002 IDA negative regulation of dendritic spine morphogenesis
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018787 efna1b ephrin A1b protein_coding Danio_rerio
ENSDARG00000030326 efna1a ephrin A1a protein_coding Danio_rerio
ENSG00000169242 EFNA1 ephrin-A1 protein_coding Homo_sapiens

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