C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ephrin-A1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169242 EFNA1 9606 + 1:155127460-155134857 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368406 EFNA1-002 155127876-155134857 protein_coding
  ENST00000368407 EFNA1-001 155127460-155134857 protein_coding
  ENST00000469878 EFNA1-003 155127888-155134486 processed_transcript
  ENST00000474413 EFNA1-004 155129562-155134307 processed_transcript
  ENST00000497282 EFNA1-005 155131204-155134125 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368406ENST00000368407ENST00000469878ENST00000474413ENST00000497282
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368406 12.791±0.00 12.249±0.00 N/A 3.171±0.00 9.515±0.00 3.983±3.19 6.372±0.00 20.444±0.00 49.048±0.00 46.701±0.00 1.063±0.62 8.978±0.95 57.058±11.14 4.806±0.00
ENST00000368407 N/A N/A 0.500±0.00 1.529±1.05 N/A 2.789±2.32 1.491±0.00 5.563±2.30 39.202±0.00 15.823±14.59 2.426±0.00 8.906±3.97 38.229±1.03 1.364±0.02
ENST00000469878 N/A 7.080±0.00 1.486±0.00 2.683±2.45 2.884±0.38 2.587±0.36 1.598±1.00 4.061±0.00 1.793±0.00 13.765±8.67 N/A 6.348±4.35 N/A 1.383±0.00
ENST00000474413 N/A N/A N/A N/A N/A N/A 0.752±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000497282 N/A N/A N/A 0.418±0.00 N/A N/A N/A 3.158±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000LV CIL_0000LV_0003 CGP 1:155078872-155134857
CIL_0000LP CIL_0000LP_0002 CGP 1:155127460-155138857

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000187 IEA activation of MAPK activity
GO:0001525 IBA angiogenesis
GO:0003180 ISS aortic valve morphogenesis
GO:0003183 ISS mitral valve morphogenesis
GO:0003199 ISS endocardial cushion to mesenchymal transition involved in heart valve formation
GO:0005102 TAS receptor binding
GO:0005515 IPI protein binding
GO:0005887 TAS integral component of plasma membrane
GO:0007267 TAS cell-cell signaling
GO:0007411 IBA axon guidance
GO:0010719 ISS negative regulation of epithelial to mesenchymal transition
GO:0014028 IEA notochord formation
GO:0016020 IEA membrane
GO:0016477 IDA cell migration
GO:0030182 IEA neuron differentiation
GO:0033628 IDA regulation of cell adhesion mediated by integrin
GO:0034446 IDA substrate adhesion-dependent cell spreading
GO:0043535 IEA regulation of blood vessel endothelial cell migration
GO:0045765 IEA regulation of angiogenesis
GO:0046658 IBA anchored component of plasma membrane
GO:0046875 IPI ephrin receptor binding
GO:0048013 IDA ephrin receptor signaling pathway
GO:0050730 ISS regulation of peptidyl-tyrosine phosphorylation
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050770 IEA regulation of axonogenesis
GO:0061002 ISS negative regulation of dendritic spine morphogenesis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018787 efna1b ephrin A1b protein_coding Danio_rerio
ENSDARG00000030326 efna1a ephrin A1a protein_coding Danio_rerio
ENSMUSG00000027954 Efna1 ephrin A1 protein_coding Mus_musculus

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