C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: platelet-derived growth factor, C polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028019 Pdgfc 10090 + 3:81036416-81214040 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029652 Pdgfc-001 81036416-81214040 protein_coding
  ENSMUST00000129285 Pdgfc-002 81037172-81214034 nonsense_mediated_decay
  ENSMUST00000143721 Pdgfc-003 81037424-81210770 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029652ENSMUST00000129285
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029652 3.747±1.35 1.547±0.24 3.291±0.14 1.115±0.54 3.216±0.75 1.043±0.18 0.498±0.26 1.982±0.33 0.225±0.11 0.568±0.11 0.311±0.08 5.505±2.23 0.773±0.49 0.817±0.26
ENSMUST00000129285 4.911±2.64 N/A 3.264±0.09 0.635±0.08 2.397±0.97 N/A 0.324±0.14 2.365±0.36 0.414±0.30 0.297±0.14 0.228±0.11 6.403±2.26 0.741±0.57 1.437±0.64

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005161 IDA platelet-derived growth factor receptor binding
GO:0005515 IEA protein binding
GO:0005576 IDA extracellular region
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007171 IDA activation of transmembrane receptor protein tyrosine kinase activity
GO:0008083 IEA growth factor activity
GO:0008284 IDA positive regulation of cell proliferation
GO:0009887 IGI organ morphogenesis
GO:0009986 IEA cell surface
GO:0042803 IEA protein homodimerization activity
GO:0045740 IEA positive regulation of DNA replication
GO:0048008 IDA platelet-derived growth factor receptor signaling pathway
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0050730 IDA regulation of peptidyl-tyrosine phosphorylation
GO:0051781 IEA positive regulation of cell division
GO:0070062 IEA extracellular vesicular exosome
GO:0071230 IDA cellular response to amino acid stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077588 PDGFC platelet derived growth factor C protein_coding Danio_rerio
ENSG00000145431 PDGFC platelet derived growth factor C protein_coding Homo_sapiens

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