C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: IQ motif containing GTPase activating protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028068 Iqgap3 10090 + 3:88082051-88121048 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000071812 Iqgap3-201 88082051-88121048 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000071812
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000071812 2.440±0.88 0.681±0.29 0.365±0.12 2.242±1.70 0.265±0.08 3.479±1.38 0.085±0.03 0.199±0.04 2.047±2.44 0.544±0.19 0.082±0.03 2.308±0.99 5.325±2.94 0.628±0.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000850 CIL_000850_0002 VISTA 3:87682625-88286876
CIL_0008JO CIL_0008JO_0002 VISTA 3:87838105-88441065

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0000187 IMP activation of MAPK activity
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0005099 IEA Ras GTPase activator activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005737 IDA cytoplasm
GO:0005911 IDA cell-cell junction
GO:0007265 IMP Ras protein signal transduction
GO:0008361 IMP regulation of cell size
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0016328 IDA lateral plasma membrane
GO:0017016 IPI Ras GTPase binding
GO:0017048 IPI Rho GTPase binding
GO:0032320 IEA positive regulation of Ras GTPase activity
GO:0033601 IMP positive regulation of mammary gland epithelial cell proliferation
GO:0070371 IMP ERK1 and ERK2 cascade
GO:0070856 IEA myosin VI light chain binding
GO:0071310 IDA cellular response to organic substance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089999 IQGAP3 IQ motif containing GTPase activating protein 3 protein_coding Danio_rerio
ENSG00000183856 IQGAP3 IQ motif containing GTPase activating protein 3 protein_coding Homo_sapiens

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