C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: IQ motif containing GTPase activating protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000183856 IQGAP3 9606 - 1:156525405-156572604 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361170 IQGAP3-001 156525405-156572540 protein_coding
  ENST00000476565 IQGAP3-004 156536831-156538861 processed_transcript
  ENST00000491900 IQGAP3-002 156525405-156572604 nonsense_mediated_decay
  ENST00000498755 IQGAP3-003 156537176-156539465 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361170ENST00000491900
Transcript ID Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361170 0.076±0.00 N/A 0.490±0.00 0.106±0.00 N/A N/A 0.075±0.00 0.025±0.00 3.473±4.37 1.359±0.20 0.859±0.08
ENST00000491900 N/A 0.086±0.08 0.353±0.00 0.063±0.00 0.029±0.00 0.030±0.00 N/A N/A 0.101±0.00 N/A 1.354±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008JO CIL_0008JO_0001 VISTA 1:156202708-156805613
CIL_000850 CIL_000850_0001 VISTA 1:156360457-156965492

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0000187 IEA activation of MAPK activity
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0005099 IEA Ras GTPase activator activity
GO:0005515 IEA protein binding
GO:0005516 IPI calmodulin binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0005911 IEA cell-cell junction
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007265 IEA Ras protein signal transduction
GO:0008361 IEA regulation of cell size
GO:0010628 IEA positive regulation of gene expression
GO:0010629 IEA negative regulation of gene expression
GO:0016328 IEA lateral plasma membrane
GO:0017016 IEA Ras GTPase binding
GO:0017048 IEA Rho GTPase binding
GO:0032318 IEA regulation of Ras GTPase activity
GO:0032320 IEA positive regulation of Ras GTPase activity
GO:0033601 IEA positive regulation of mammary gland epithelial cell proliferation
GO:0070371 IEA ERK1 and ERK2 cascade
GO:0070856 IPI myosin VI light chain binding
GO:0071310 IEA cellular response to organic substance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089999 IQGAP3 IQ motif containing GTPase activating protein 3 protein_coding Danio_rerio
ENSMUSG00000028068 Iqgap3 IQ motif containing GTPase activating protein 3 protein_coding Mus_musculus

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