C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: retinal pigment epithelium 65
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028174 Rpe65 10090 + 3:159599233-159624799 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029824 Rpe65-201 159599233-159624799 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainLiverTestisENSMUST00000029824
Transcript ID Adipose Bladder Brain Liver Testis
ENSMUST00000029824 0.032±0.00 0.056±0.02 0.067±0.00 0.006±0.00 0.045±0.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001895 IEA retina homeostasis
GO:0004744 IMP retinal isomerase activity
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IEA plasma membrane
GO:0007468 IMP regulation of rhodopsin gene expression
GO:0007601 IMP visual perception
GO:0008286 IMP insulin receptor signaling pathway
GO:0042572 IEA retinol metabolic process
GO:0042574 IMP retinal metabolic process
GO:0044297 IEA cell body
GO:0046872 IEA metal ion binding
GO:0050908 IEA detection of light stimulus involved in visual perception
GO:0052884 IEA all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity
GO:0052885 IEA all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
GO:0060041 IMP retina development in camera-type eye
GO:0060042 IMP retina morphogenesis in camera-type eye
GO:0071257 IMP cellular response to electrical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007480 rpe65a retinal pigment epithelium-specific protein 65a protein_coding Danio_rerio
ENSDARG00000054420 rpe65c retinal pigment epithelium-specific protein 65c protein_coding Danio_rerio
ENSDARG00000094752 rpe65b retinal pigment epithelium-specific protein 65b protein_coding Danio_rerio
ENSG00000116745 RPE65 retinal pigment epithelium-specific protein 65kDa protein_coding Homo_sapiens

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