C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: retinal pigment epithelium-specific protein 65kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116745 RPE65 9606 - 1:68428822-68449959 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262340 RPE65-001 68428822-68449959 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastLiverOvaryPlacentaTestisENST00000262340
Transcript ID Adrenal Brain Breast Liver Ovary Placenta Testis
ENST00000262340 0.048±0.00 0.819±0.52 0.017±0.00 0.018±0.00 0.049±0.03 0.015±0.00 0.041±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000038 CIL_000038_0002 CGP 1:68428822-68497221

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0001895 IMP retina homeostasis
GO:0004744 IEA retinal isomerase activity
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0006776 TAS vitamin A metabolic process
GO:0007468 IEA regulation of rhodopsin gene expression
GO:0007601 TAS visual perception
GO:0007603 TAS phototransduction, visible light
GO:0008286 IEA insulin receptor signaling pathway
GO:0042572 IEA retinol metabolic process
GO:0042574 IEA retinal metabolic process
GO:0044297 IEA cell body
GO:0046872 IEA metal ion binding
GO:0050908 IMP detection of light stimulus involved in visual perception
GO:0052884 IEA all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity
GO:0052885 IEA all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
GO:0060041 IEA retina development in camera-type eye
GO:0060042 IEA retina morphogenesis in camera-type eye
GO:0071257 IEA cellular response to electrical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007480 rpe65a retinal pigment epithelium-specific protein 65a protein_coding Danio_rerio
ENSDARG00000054420 rpe65c retinal pigment epithelium-specific protein 65c protein_coding Danio_rerio
ENSDARG00000094752 rpe65b retinal pigment epithelium-specific protein 65b protein_coding Danio_rerio
ENSMUSG00000028174 Rpe65 retinal pigment epithelium 65 protein_coding Mus_musculus

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