Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	polymerase (DNA directed), epsilon 3 (p17 subunit)
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000028394	Pole3	10090	-	4:62522649-62525068	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000030091		Pole3-001	62522649-62525068	protein_coding
	ENSMUST00000128100		Pole3-002	62522649-62525068	nonsense_mediated_decay
	ENSMUST00000129930		Pole3-003	62524335-62525038	retained_intron

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENSMUST00000030091	14.160±0.52	16.190±3.02	13.923±0.87	18.144±1.86	8.983±0.91	7.630±1.36	6.157±0.09	11.248±0.59	19.008±14.70	10.610±1.33	8.639±0.43	16.647±5.31	32.739±9.16	45.532±28.84
ENSMUST00000128100	N/A	1.901±0.00	N/A	N/A	1.059±0.00	0.892±0.01	N/A	N/A	0.574±0.00	N/A	N/A	1.414±0.00	N/A	N/A
ENSMUST00000129930	N/A	19.050±5.55	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0004CD	CIL_0004CD_0002	CGP	4:62509169-62525068
CIL_0004CZ	CIL_0004CZ_0002	CGP	4:62522649-62547993

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0003887	IEA	DNA-directed DNA polymerase activity
GO:0005515	IPI	protein binding
GO:0005622	IEA	intracellular
GO:0008622	ISS	epsilon DNA polymerase complex
GO:0043565	IEA	sequence-specific DNA binding
GO:0046982	IEA	protein heterodimerization activity
GO:0071897	IEA	DNA biosynthetic process

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000008551	pole3	polymerase (DNA directed), epsilon 3 (p17 subunit)	protein_coding	Danio_rerio
ENSG00000148229	POLE3	polymerase (DNA directed), epsilon 3, accessory subunit	protein_coding	Homo_sapiens

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