C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, AMP-activated, alpha 2 catalytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028518 Prkaa2 10090 - 4:105029874-105109890 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030243 Prkaa2-001 105029874-105109890 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030243
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030243 2.265±0.21 1.876±0.58 8.770±0.00 3.459±0.36 4.969±2.97 15.140±1.81 15.004±1.45 18.856±2.32 5.148±5.19 4.478±0.44 19.869±11.23 1.895±0.56 0.712±0.31 0.254±0.08

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003682 IDA chromatin binding
GO:0004674 IMP protein serine/threonine kinase activity
GO:0004679 TAS AMP-activated protein kinase activity
GO:0004712 ISO protein serine/threonine/tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006633 IEA fatty acid biosynthetic process
GO:0006695 IEA cholesterol biosynthetic process
GO:0006914 IEA autophagy
GO:0006950 IMP response to stress
GO:0008610 IDA lipid biosynthetic process
GO:0010508 IMP positive regulation of autophagy
GO:0016055 IEA Wnt signaling pathway
GO:0031669 IDA cellular response to nutrient levels
GO:0032007 IMP negative regulation of TOR signaling
GO:0035174 IDA histone serine kinase activity
GO:0035404 IDA histone-serine phosphorylation
GO:0042149 IDA cellular response to glucose starvation
GO:0042593 IMP glucose homeostasis
GO:0042752 IMP regulation of circadian rhythm
GO:0043066 IMP negative regulation of apoptotic process
GO:0045821 ISS positive regulation of glycolytic process
GO:0046872 IEA metal ion binding
GO:0047322 IEA [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
GO:0048511 IEA rhythmic process
GO:0050405 IEA [acetyl-CoA carboxylase] kinase activity
GO:0055089 ISS fatty acid homeostasis
GO:2000505 ISS regulation of energy homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060641 prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit protein_coding Danio_rerio
ENSG00000162409 PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit protein_coding Homo_sapiens

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