C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: epidermal growth factor receptor pathway substrate 15
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028552 Eps15 10090 + 4:109280268-109387817 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030281 Eps15-002 109343059-109386566 protein_coding
  ENSMUST00000102729 Eps15-001 109280268-109387817 protein_coding
  ENSMUST00000126015 Eps15-006 109343253-109366874 retained_intron
  ENSMUST00000132165 Eps15-011 109280412-109385465 protein_coding
  ENSMUST00000141751 Eps15-004 109309151-109313211 retained_intron
  ENSMUST00000150755 Eps15-003 109304465-109305927 retained_intron
  ENSMUST00000175776 Eps15-005 109280412-109385465 protein_coding
  ENSMUST00000176251 Eps15-008 109280303-109385687 nonsense_mediated_decay
  ENSMUST00000177089 Eps15-007 109280376-109312908 protein_coding
  ENSMUST00000177140 Eps15-009 109370592-109382858 processed_transcript
  ENSMUST00000177192 Eps15-010 109370548-109385783 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030281ENSMUST00000102729ENSMUST00000132165ENSMUST00000175776ENSMUST00000176251ENSMUST00000177192
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030281 2.411±0.49 1.182±0.04 N/A 12.321±5.40 2.963±0.71 1.837±0.39 1.708±0.03 2.492±0.40 2.315±1.25 5.474±0.72 N/A 2.495±0.59 3.412±0.13 4.032±0.55
ENSMUST00000102729 4.089±1.65 2.480±0.75 13.625±0.77 8.176±2.48 4.337±2.35 1.848±0.81 2.976±0.53 5.691±1.36 8.239±6.66 8.004±1.37 10.669±0.38 4.817±4.65 11.178±0.99 10.109±0.31
ENSMUST00000132165 N/A N/A N/A 10.097±0.00 N/A N/A N/A N/A N/A N/A N/A 9.788±0.00 7.796±0.63 15.830±0.00
ENSMUST00000175776 3.469±0.87 0.870±0.00 N/A N/A 5.755±2.71 N/A 1.882±0.61 N/A 0.862±0.00 N/A 5.855±0.22 2.466±1.91 7.076±3.11 10.346±0.56
ENSMUST00000176251 N/A N/A N/A N/A N/A 0.488±0.00 N/A N/A N/A N/A N/A 3.445±0.00 6.146±1.82 6.244±0.00
ENSMUST00000177192 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.423±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0005886 IDA plasma membrane
GO:0005905 IDA coated pit
GO:0006895 ISS Golgi to endosome transport
GO:0006897 IEA endocytosis
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0017124 IEA SH3 domain binding
GO:0030122 IDA AP-2 adaptor complex
GO:0030132 IDA clathrin coat of coated pit
GO:0030136 IDA clathrin-coated vesicle
GO:0031593 ISS polyubiquitin binding
GO:0042802 IPI identical protein binding
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0048268 IEA clathrin coat assembly
GO:0060170 IDA ciliary membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078216 eps15 epidermal growth factor receptor pathway substrate 15 protein_coding Danio_rerio
ENSG00000085832 EPS15 epidermal growth factor receptor pathway substrate 15 protein_coding Homo_sapiens

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