C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: epidermal growth factor receptor pathway substrate 15
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000085832 EPS15 9606 - 1:51354263-51519328 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371727 EPS15-003 51457536-51519245 retained_intron
  ENST00000371730 EPS15-002 51354263-51519241 protein_coding
  ENST00000371733 EPS15-001 51354263-51519328 protein_coding
  ENST00000464478 EPS15-004 51458396-51465326 processed_transcript
  ENST00000465467 EPS15-005 51461123-51519227 nonsense_mediated_decay
  ENST00000471391 EPS15-006 51460944-51519254 retained_intron
  ENST00000478657 EPS15-007 51394419-51401199 retained_intron
  ENST00000486505 EPS15-008 51394212-51403451 retained_intron
  ENST00000493793 EPS15-009 51403429-51422104 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371730ENST00000371733
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371730 N/A N/A 2.265±0.00 5.326±0.00 N/A N/A 1.208±0.00 N/A N/A N/A N/A N/A 2.472±1.24 13.548±0.00
ENST00000371733 16.816±0.00 13.115±0.00 2.109±0.00 20.986±0.00 13.085±1.21 8.523±1.53 8.321±2.85 8.297±1.77 8.052±4.36 9.892±2.97 10.518±8.51 6.661±3.11 5.971±1.82 13.998±9.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006W8 CIL_0006W8_0002 CGP 1:51287258-51519328

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005905 TAS coated pit
GO:0006895 IMP Golgi to endosome transport
GO:0006897 IEA endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008283 TAS cell proliferation
GO:0015031 IEA protein transport
GO:0016020 IDA membrane
GO:0016050 TAS vesicle organization
GO:0017124 IEA SH3 domain binding
GO:0030122 IEA AP-2 adaptor complex
GO:0030132 IEA clathrin coat of coated pit
GO:0030136 IEA clathrin-coated vesicle
GO:0031593 IDA polyubiquitin binding
GO:0032456 IC endocytic recycling
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0042802 IEA identical protein binding
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0048268 IDA clathrin coat assembly
GO:0060170 IEA ciliary membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078216 eps15 epidermal growth factor receptor pathway substrate 15 protein_coding Danio_rerio
ENSMUSG00000028552 Eps15 epidermal growth factor receptor pathway substrate 15 protein_coding Mus_musculus

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