C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: endothelin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028635 Edn2 10090 + 4:120161206-120167360 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030384 Edn2-001 120161206-120167360 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000030384
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000030384 0.272±0.02 0.028±0.00 0.068±0.02 0.045±0.02 0.074±0.05 13.389±0.70 0.122±0.09 0.027±0.01 0.037±0.02 0.209±0.10 6.023±5.26 1.424±1.84 0.020±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000876 CIL_000876_0002 VISTA 4:120091603-120693946
CIL_0009C0 CIL_0009C0_0002 VISTA 4:120091667-120696253

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001516 IDA prostaglandin biosynthetic process
GO:0001659 IMP temperature homeostasis
GO:0002690 IEA positive regulation of leukocyte chemotaxis
GO:0003100 IEA regulation of systemic arterial blood pressure by endothelin
GO:0005179 IEA hormone activity
GO:0005615 IEA extracellular space
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0008284 IEA positive regulation of cell proliferation
GO:0010460 IEA positive regulation of heart rate
GO:0014824 IEA artery smooth muscle contraction
GO:0014826 IEA vein smooth muscle contraction
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019229 IEA regulation of vasoconstriction
GO:0019722 IEA calcium-mediated signaling
GO:0030593 IEA neutrophil chemotaxis
GO:0042116 IEA macrophage activation
GO:0042310 IEA vasoconstriction
GO:0045987 IDA positive regulation of smooth muscle contraction
GO:0048016 IEA inositol phosphate-mediated signaling
GO:0048246 IEA macrophage chemotaxis
GO:0048286 IMP lung alveolus development
GO:0060585 IMP positive regulation of prostaglandin-endoperoxide synthase activity
GO:0097009 IMP energy homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070578 edn2 endothelin 2 protein_coding Danio_rerio
ENSG00000127129 EDN2 endothelin 2 protein_coding Homo_sapiens

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