C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 2B, subunit 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028683 Eif2b3 10090 + 4:117019402-117087306 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000070610 Eif2b3-002 117022155-117086845 protein_coding
  ENSMUST00000106447 Eif2b3-201 117019408-117073260 protein_coding
  ENSMUST00000106448 Eif2b3-001 117019402-117086852 protein_coding
  ENSMUST00000129587 Eif2b3-006 117081281-117086848 processed_transcript
  ENSMUST00000135121 Eif2b3-004 117044476-117059325 processed_transcript
  ENSMUST00000151760 Eif2b3-005 117066471-117074300 processed_transcript
  ENSMUST00000155181 Eif2b3-003 117067463-117087306 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000070610ENSMUST00000106447ENSMUST00000106448ENSMUST00000135121ENSMUST00000155181
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000070610 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.282±0.00 N/A N/A
ENSMUST00000106447 N/A 0.232±0.08 N/A N/A 0.225±0.01 0.306±0.13 N/A N/A 0.459±0.30 0.283±0.02 N/A 0.365±0.07 0.648±0.00 0.255±0.00
ENSMUST00000106448 10.437±2.55 2.959±0.77 10.194±1.13 10.300±1.31 5.806±2.96 2.499±0.78 3.662±1.22 5.301±0.34 8.191±6.05 4.226±0.29 7.164±0.99 7.192±2.68 10.611±3.50 3.675±0.28
ENSMUST00000135121 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.892±0.00
ENSMUST00000155181 1.050±0.07 0.311±0.04 N/A N/A 0.585±0.07 0.340±0.17 N/A N/A 0.357±0.00 0.599±0.00 N/A 0.975±0.37 N/A 0.443±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003743 ISS translation initiation factor activity
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005851 ISS eukaryotic translation initiation factor 2B complex
GO:0006413 ISS translational initiation
GO:0006417 IEA regulation of translation
GO:0008135 ISS translation factor activity, nucleic acid binding
GO:0009408 IEA response to heat
GO:0009749 IEA response to glucose
GO:0014003 ISS oligodendrocyte development
GO:0016779 IEA nucleotidyltransferase activity
GO:0032057 IEA negative regulation of translational initiation in response to stress
GO:0043434 IEA response to peptide hormone
GO:0043547 ISS positive regulation of GTPase activity
GO:0051716 ISS cellular response to stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018106 eif2b3 eukaryotic translation initiation factor 2B, subunit 3 gamma protein_coding Danio_rerio
ENSG00000070785 EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa protein_coding Homo_sapiens

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