C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070785 EIF2B3 9606 - 1:44850522-44986722 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360403 EIF2B3-001 44850778-44986610 protein_coding
  ENST00000372182 EIF2B3-006 44940629-44986596 protein_coding
  ENST00000372183 EIF2B3-002 44874527-44986587 protein_coding
  ENST00000439363 EIF2B3-008 44850776-44926655 protein_coding
  ENST00000477953 EIF2B3-003 44926628-44986586 processed_transcript
  ENST00000480675 EIF2B3-004 44924958-44986599 processed_transcript
  ENST00000486491 EIF2B3-009 44863004-44875622 processed_transcript
  ENST00000487532 EIF2B3-007 44958561-44986595 processed_transcript
  ENST00000497010 EIF2B3-005 44969988-44986595 processed_transcript
  ENST00000620860 EIF2B3-201 44850522-44986722 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360403ENST00000372182ENST00000372183ENST00000439363ENST00000480675ENST00000497010ENST00000620860
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360403 7.132±0.00 9.806±0.00 N/A 7.276±2.80 18.680±0.00 8.681±0.00 8.811±5.77 4.514±4.11 7.636±0.00 3.801±3.14 11.669±9.96 7.486±4.61 6.007±1.58 20.190±1.44
ENST00000372182 N/A N/A 2.063±0.00 N/A 2.312±0.00 1.626±0.00 N/A N/A 1.179±0.00 N/A N/A N/A N/A N/A
ENST00000372183 2.111±0.00 N/A 1.456±0.00 N/A 2.449±0.00 1.605±0.00 N/A 2.015±0.00 1.968±0.00 3.498±0.00 3.974±0.00 2.236±1.30 1.095±0.00 N/A
ENST00000439363 N/A N/A N/A N/A N/A 4.093±0.00 N/A N/A 4.561±0.00 N/A N/A N/A N/A N/A
ENST00000480675 N/A N/A N/A N/A N/A 1.027±0.00 N/A N/A N/A N/A N/A 1.222±0.00 N/A N/A
ENST00000497010 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.547±0.00 N/A N/A N/A
ENST00000620860 N/A N/A N/A N/A N/A N/A N/A 0.760±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000637 CIL_000637_0002 CGP 1:44819844-44986722

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003743 IDA translation initiation factor activity
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005851 IDA eukaryotic translation initiation factor 2B complex
GO:0006412 TAS translation
GO:0006413 IDA translational initiation
GO:0006417 IEA regulation of translation
GO:0008135 IDA translation factor activity, nucleic acid binding
GO:0009058 IEA biosynthetic process
GO:0009408 ISS response to heat
GO:0009749 ISS response to glucose
GO:0010467 TAS gene expression
GO:0014003 IMP oligodendrocyte development
GO:0016779 IEA nucleotidyltransferase activity
GO:0032057 ISS negative regulation of translational initiation in response to stress
GO:0043434 ISS response to peptide hormone
GO:0043547 IDA positive regulation of GTPase activity
GO:0044267 TAS cellular protein metabolic process
GO:0051716 IDA cellular response to stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018106 eif2b3 eukaryotic translation initiation factor 2B, subunit 3 gamma protein_coding Danio_rerio
ENSMUSG00000028683 Eif2b3 eukaryotic translation initiation factor 2B, subunit 3 protein_coding Mus_musculus

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