C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific methyltransferase 2E
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029004 Kmt2e 10090 + 5:23434441-23504235 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000094962 Kmt2e-001 23434441-23504235 protein_coding
  ENSMUST00000115128 Kmt2e-002 23434449-23504235 protein_coding
  ENSMUST00000126586 Kmt2e-004 23492421-23500487 nonsense_mediated_decay
  ENSMUST00000146375 Kmt2e-003 23485501-23496208 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000094962ENSMUST00000115128
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000094962 9.060±1.92 9.773±2.60 8.746±1.69 17.671±11.87 10.708±3.64 8.049±2.90 4.325±0.78 7.648±1.31 3.759±1.36 12.191±1.72 2.918±1.32 10.015±4.09 3.724±0.97 5.864±0.29
ENSMUST00000115128 1.374±0.17 2.856±0.71 N/A 4.579±0.00 1.467±0.13 2.180±0.41 1.141±0.07 1.730±0.39 0.983±0.14 1.933±0.14 0.942±0.00 1.882±0.14 1.507±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00040Y CIL_00040Y_0002 CGP 5:23434441-23616571

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002446 IMP neutrophil mediated immunity
GO:0003713 ISS transcription coactivator activity
GO:0006306 IMP DNA methylation
GO:0006351 IEA transcription, DNA-templated
GO:0007050 IEA cell cycle arrest
GO:0008270 IEA zinc ion binding
GO:0019899 IEA enzyme binding
GO:0030218 IMP erythrocyte differentiation
GO:0030854 IEA positive regulation of granulocyte differentiation
GO:0042119 IMP neutrophil activation
GO:0042800 ISS histone methyltransferase activity (H3-K4 specific)
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0048384 ISS retinoic acid receptor signaling pathway
GO:0051568 ISS histone H3-K4 methylation
GO:0070688 ISS MLL5-L complex
GO:0071300 ISS cellular response to retinoic acid

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007523 kmt2e lysine (K)-specific methyltransferase 2E protein_coding Danio_rerio
ENSG00000005483 KMT2E lysine (K)-specific methyltransferase 2E protein_coding Homo_sapiens

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