C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanine nucleotide binding protein (G protein), beta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029064 Gnb1 10090 + 4:155491361-155559269 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030940 Gnb1-001 155491370-155559269 protein_coding
  ENSMUST00000105616 Gnb1-004 155491364-155559269 protein_coding
  ENSMUST00000165335 Gnb1-201 155491361-155559269 protein_coding
  ENSMUST00000175688 Gnb1-005 155522636-155541214 retained_intron
  ENSMUST00000175705 Gnb1-006 155542928-155555205 retained_intron
  ENSMUST00000176308 Gnb1-007 155553224-155557653 retained_intron
  ENSMUST00000176411 Gnb1-002 155492909-155543087 protein_coding
  ENSMUST00000176637 Gnb1-008 155527453-155559267 protein_coding
  ENSMUST00000177094 Gnb1-003 155522462-155555136 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030940ENSMUST00000105616ENSMUST00000165335ENSMUST00000175705ENSMUST00000176308ENSMUST00000176411ENSMUST00000176637
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030940 23.993±4.67 35.469±6.06 14.372±3.73 80.111±6.22 19.529±2.86 47.320±9.92 11.903±1.66 20.046±1.78 9.761±2.82 40.085±2.43 6.125±1.46 42.008±14.88 33.198±16.27 11.308±8.16
ENSMUST00000105616 27.291±5.29 17.775±2.20 30.780±2.76 47.513±0.34 24.371±1.67 48.927±5.13 8.957±2.95 18.589±3.36 11.251±6.31 46.730±6.02 2.559±0.62 35.972±11.47 36.350±19.76 10.751±0.50
ENSMUST00000165335 N/A N/A 25.342±2.25 28.896±8.73 N/A 42.884±17.31 N/A N/A 11.362±3.80 N/A 1.814±0.00 27.970±9.89 28.984±14.32 12.203±6.22
ENSMUST00000175705 94.630±16.76 132.984±42.37 N/A N/A 152.668±42.81 128.078±31.80 30.682±4.19 56.052±6.26 28.192±7.97 111.702±9.13 N/A 150.544±47.04 121.185±20.54 60.710±7.66
ENSMUST00000176308 113.814±22.43 N/A 49.099±6.76 160.138±48.67 94.643±6.46 94.245±24.55 34.553±2.87 56.764±3.32 34.244±14.07 N/A N/A 203.369±26.26 134.088±29.52 61.638±33.89
ENSMUST00000176411 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 102.534±0.00 202.177±44.75 42.057±0.00
ENSMUST00000176637 47.164±8.74 55.097±15.79 N/A 52.626±0.65 40.909±7.82 N/A 11.946±5.09 35.566±4.92 10.553±2.13 49.950±9.95 2.360±1.05 43.674±13.17 35.172±6.06 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QV CIL_0007QV_0002 VISTA 4:154934679-155536167

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001664 IEA G-protein coupled receptor binding
GO:0001750 IDA photoreceptor outer segment
GO:0001917 IEA photoreceptor inner segment
GO:0003924 ISA GTPase activity
GO:0004871 IEA signal transducer activity
GO:0005765 IEA lysosomal membrane
GO:0005834 IPI heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0007200 IDA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007603 ISA phototransduction, visible light
GO:0008283 IDA cell proliferation
GO:0010659 ISO cardiac muscle cell apoptotic process
GO:0030425 IEA dendrite
GO:0030507 ISO spectrin binding
GO:0031702 IEA type 1 angiotensin receptor binding
GO:0031982 IEA vesicle
GO:0032403 ISO protein complex binding
GO:0042622 IEA photoreceptor outer segment membrane
GO:0044297 IEA cell body
GO:0050909 IDA sensory perception of taste
GO:0051020 IEA GTPase binding
GO:0060041 IMP retina development in camera-type eye
GO:0070062 IEA extracellular vesicular exosome
GO:0071456 ISO cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005944 gnb1b guanine nucleotide binding protein (G protein), beta polypeptide 1b protein_coding Danio_rerio
ENSDARG00000060360 gnb1b guanine nucleotide binding protein (G protein), beta polypeptide 1b protein_coding Danio_rerio
ENSDARG00000090454 gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a protein_coding Danio_rerio
ENSG00000078369 GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 protein_coding Homo_sapiens

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