C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dishevelled, dsh homolog 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029071 Dvl1 10090 + 4:155847402-155859303 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030948 Dvl1-001 155847402-155859303 protein_coding
  ENSMUST00000129450 Dvl1-004 155854572-155856232 retained_intron
  ENSMUST00000133184 Dvl1-005 155847566-155859303 retained_intron
  ENSMUST00000140529 Dvl1-006 155853410-155853951 processed_transcript
  ENSMUST00000141539 Dvl1-002 155847586-155859303 retained_intron
  ENSMUST00000143457 Dvl1-003 155847671-155859303 retained_intron
  ENSMUST00000156997 Dvl1-007 155847466-155859302 retained_intron
  ENSMUST00000168552 Dvl1-201 155847461-155858878 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030948ENSMUST00000129450ENSMUST00000141539ENSMUST00000143457ENSMUST00000156997ENSMUST00000168552
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030948 29.712±7.08 11.929±1.06 18.004±0.98 10.688±2.67 24.902±14.20 18.136±6.66 13.791±3.20 42.168±7.64 14.505±6.57 16.647±4.92 33.916±2.12 21.121±9.84 9.978±5.97 27.548±6.84
ENSMUST00000129450 N/A N/A N/A 126.050±0.00 N/A N/A N/A N/A N/A N/A N/A 81.285±0.00 45.266±5.45 97.032±0.00
ENSMUST00000141539 9.899±1.46 12.866±1.93 8.704±0.75 N/A 11.396±1.96 11.932±1.01 N/A N/A 4.634±2.11 8.740±1.69 N/A 14.207±3.57 3.118±0.30 N/A
ENSMUST00000143457 7.494±0.00 12.564±2.16 N/A 29.743±9.86 10.249±0.82 N/A N/A 9.850±0.87 8.975±4.70 9.215±0.75 N/A 14.675±3.62 6.284±0.21 10.622±0.97
ENSMUST00000156997 N/A N/A N/A 6.570±1.37 N/A N/A N/A N/A N/A N/A N/A 2.124±0.00 N/A 5.738±1.73
ENSMUST00000168552 13.391±1.35 29.852±5.39 9.305±0.00 22.656±9.85 27.411±5.11 14.494±4.41 5.947±0.00 10.640±0.00 12.557±3.30 18.589±6.33 18.111±2.22 17.394±5.01 9.394±4.78 15.209±3.76

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003D7 CIL_0003D7_0002 CGP 4:155839680-155859303

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001505 IMP regulation of neurotransmitter levels
GO:0001932 IGI regulation of protein phosphorylation
GO:0001933 IGI negative regulation of protein phosphorylation
GO:0005109 IBA frizzled binding
GO:0005515 IPI protein binding
GO:0005874 IBA microtubule
GO:0005938 IBA cell cortex
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006469 IEA negative regulation of protein kinase activity
GO:0007269 IGI neurotransmitter secretion
GO:0007409 IDA axonogenesis
GO:0007411 IDA axon guidance
GO:0007528 IGI neuromuscular junction development
GO:0010976 IMP positive regulation of neuron projection development
GO:0015630 IDA microtubule cytoskeleton
GO:0016020 NAS membrane
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016055 TAS Wnt signaling pathway
GO:0016328 IEA lateral plasma membrane
GO:0019899 IEA enzyme binding
GO:0019901 IBA protein kinase binding
GO:0021915 IEA neural tube development
GO:0022007 IGI convergent extension involved in neural plate elongation
GO:0030136 IDA clathrin-coated vesicle
GO:0030177 IEA positive regulation of Wnt signaling pathway
GO:0030424 IDA axon
GO:0030425 IBA dendrite
GO:0030426 IBA growth cone
GO:0031122 IDA cytoplasmic microtubule organization
GO:0031410 IEA cytoplasmic vesicle
GO:0032091 IEA negative regulation of protein binding
GO:0032436 IEA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034504 IEA protein localization to nucleus
GO:0035176 IMP social behavior
GO:0035372 IGI protein localization to microtubule
GO:0035556 IEA intracellular signal transduction
GO:0042802 IEA identical protein binding
GO:0043025 IBA neuronal cell body
GO:0043113 IGI receptor clustering
GO:0045202 IDA synapse
GO:0045893 IBA positive regulation of transcription, DNA-templated
GO:0048365 IBA Rac GTPase binding
GO:0048668 IDA collateral sprouting
GO:0048675 IDA axon extension
GO:0048813 IMP dendrite morphogenesis
GO:0050808 IGI synapse organization
GO:0060029 IGI convergent extension involved in organogenesis
GO:0060070 IGI canonical Wnt signaling pathway
GO:0060071 IDA Wnt signaling pathway, planar cell polarity pathway
GO:0060134 IMP prepulse inhibition
GO:0071340 IMP skeletal muscle acetylcholine-gated channel clustering
GO:0090103 IGI cochlea morphogenesis
GO:0090179 IGI planar cell polarity pathway involved in neural tube closure
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010515 DVL1 (1 of 3) dishevelled segment polarity protein 1 protein_coding Danio_rerio
ENSDARG00000055552 dvl1b dishevelled, dsh homolog 1b (Drosophila) protein_coding Danio_rerio
ENSDARG00000095919 DVL1 (3 of 3) dishevelled segment polarity protein 1 protein_coding Danio_rerio
ENSG00000107404 DVL1 dishevelled segment polarity protein 1 protein_coding Homo_sapiens

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