C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dishevelled, dsh homolog 1 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000030948 Dvl1-001 ENSMUSG00000029071 10090 + 4:155847402-155859303 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030948
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030948 29.712±7.08 11.929±1.06 18.004±0.98 10.688±2.67 24.902±14.20 18.136±6.66 13.791±3.20 42.168±7.64 14.505±6.57 16.647±4.92 33.916±2.12 21.121±9.84 9.978±5.97 27.548±6.84

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003D7 CIL_0003D7_0002 CGP 4:155839680-155859303

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001505 IMP regulation of neurotransmitter levels
GO:0001932 IGI regulation of protein phosphorylation
GO:0001933 IGI negative regulation of protein phosphorylation
GO:0005109 IBA frizzled binding
GO:0005515 IPI protein binding
GO:0005874 IBA microtubule
GO:0005938 IBA cell cortex
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006469 IEA negative regulation of protein kinase activity
GO:0007269 IGI neurotransmitter secretion
GO:0007409 IDA axonogenesis
GO:0007411 IDA axon guidance
GO:0007528 IGI neuromuscular junction development
GO:0010976 IMP positive regulation of neuron projection development
GO:0015630 IDA microtubule cytoskeleton
GO:0016020 NAS membrane
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016055 TAS Wnt signaling pathway
GO:0016328 IEA lateral plasma membrane
GO:0019899 IEA enzyme binding
GO:0019901 IBA protein kinase binding
GO:0021915 IEA neural tube development
GO:0022007 IGI convergent extension involved in neural plate elongation
GO:0030136 IDA clathrin-coated vesicle
GO:0030177 IEA positive regulation of Wnt signaling pathway
GO:0030424 IDA axon
GO:0030425 IBA dendrite
GO:0030426 IBA growth cone
GO:0031122 IDA cytoplasmic microtubule organization
GO:0031410 IEA cytoplasmic vesicle
GO:0032091 IEA negative regulation of protein binding
GO:0032436 IEA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034504 IEA protein localization to nucleus
GO:0035176 IMP social behavior
GO:0035372 IGI protein localization to microtubule
GO:0035556 IEA intracellular signal transduction
GO:0042802 IEA identical protein binding
GO:0043025 IBA neuronal cell body
GO:0043113 IGI receptor clustering
GO:0045202 IDA synapse
GO:0045893 IBA positive regulation of transcription, DNA-templated
GO:0048365 IBA Rac GTPase binding
GO:0048668 IDA collateral sprouting
GO:0048675 IDA axon extension
GO:0048813 IMP dendrite morphogenesis
GO:0050808 IGI synapse organization
GO:0060029 IGI convergent extension involved in organogenesis
GO:0060070 IGI canonical Wnt signaling pathway
GO:0060071 IDA Wnt signaling pathway, planar cell polarity pathway
GO:0060134 IMP prepulse inhibition
GO:0071340 IMP skeletal muscle acetylcholine-gated channel clustering
GO:0090103 IGI cochlea morphogenesis
GO:0090179 IGI planar cell polarity pathway involved in neural tube closure
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000012450 dvl2-201 protein_coding Danio_rerio 5e-36 158
ENST00000378888 DVL1-004 protein_coding Homo_sapiens 0 2473
ENST00000378891 DVL1-001 protein_coding Homo_sapiens 0 1435
ENST00000472445 DVL1-005 retained_intron Homo_sapiens 0 497
ENST00000610709 DVL1-201 protein_coding Homo_sapiens 0 878

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