C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: epiregulin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029377 Ereg 10090 + 5:91074617-91093649 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031324 Ereg-201 91074617-91093649 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031324
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031324 0.010±0.00 0.038±0.00 0.949±0.43 0.009±0.00 0.078±0.03 2.460±0.13 0.032±0.02 0.028±0.01 0.083±0.03 0.628±0.57 0.014±0.00 0.577±0.29 0.012±0.01 0.011±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006SO CIL_0006SO_0002 CGP 5:91027464-91093649
CIL_000364 CIL_000364_0002 CGP 5:91074617-91148432

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001550 ISS ovarian cumulus expansion
GO:0001556 ISS oocyte maturation
GO:0001819 IMP positive regulation of cytokine production
GO:0005154 IDA epidermal growth factor receptor binding
GO:0005615 ISS extracellular space
GO:0005886 IEA plasma membrane
GO:0007143 ISS female meiotic division
GO:0007173 IDA epidermal growth factor receptor signaling pathway
GO:0007267 ISS cell-cell signaling
GO:0008083 IEA growth factor activity
GO:0008284 ISS positive regulation of cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0009299 ISS mRNA transcription
GO:0009653 TAS anatomical structure morphogenesis
GO:0009887 TAS organ morphogenesis
GO:0016021 IEA integral component of membrane
GO:0019221 ISS cytokine-mediated signaling pathway
GO:0030728 ISS ovulation
GO:0042108 ISS positive regulation of cytokine biosynthetic process
GO:0042327 ISS positive regulation of phosphorylation
GO:0042700 ISS luteinizing hormone signaling pathway
GO:0043434 IEA response to peptide hormone
GO:0043616 ISS keratinocyte proliferation
GO:0045089 IMP positive regulation of innate immune response
GO:0045410 IMP positive regulation of interleukin-6 biosynthetic process
GO:0045740 ISS positive regulation of DNA replication
GO:0045741 ISS positive regulation of epidermal growth factor-activated receptor activity
GO:0045840 IDA positive regulation of mitosis
GO:0045860 ISS positive regulation of protein kinase activity
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0048146 ISS positive regulation of fibroblast proliferation
GO:0048160 ISS primary follicle stage
GO:0048661 ISS positive regulation of smooth muscle cell proliferation
GO:0051151 ISS negative regulation of smooth muscle cell differentiation
GO:0051781 IEA positive regulation of cell division

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000124882 EREG epiregulin protein_coding Homo_sapiens

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