C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: amphiregulin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029378 Areg 10090 + 5:91139615-91148432 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031325 Areg-201 91139615-91148432 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031325
Transcript ID Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031325 0.858±0.30 0.055±0.01 118.532±77.76 21.872±10.64 0.049±0.02 0.026±0.02 6.607±5.57 0.039±0.00 2.446±1.22 0.119±0.06 0.034±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000364 CIL_000364_0002 CGP 5:91074617-91148432
CIL_00036A CIL_00036A_0002 CGP 5:91139615-91402994

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005125 IEA cytokine activity
GO:0005154 IEA epidermal growth factor receptor binding
GO:0005615 IEA extracellular space
GO:0005622 IDA intracellular
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0007173 IEA epidermal growth factor receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0008083 IEA growth factor activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0009986 IEA cell surface
GO:0014009 IEA glial cell proliferation
GO:0014070 IEA response to organic cyclic compound
GO:0016021 IEA integral component of membrane
GO:0031175 IEA neuron projection development
GO:0032355 IDA response to estradiol
GO:0042327 IEA positive regulation of phosphorylation
GO:0042542 IEA response to hydrogen peroxide
GO:0043434 IEA response to peptide hormone
GO:0045668 IEA negative regulation of osteoblast differentiation
GO:0045740 IEA positive regulation of DNA replication
GO:0051384 IEA response to glucocorticoid
GO:0051591 IEA response to cAMP
GO:0060598 IMP dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
GO:0060744 IMP mammary gland branching involved in thelarche
GO:0060749 IGI mammary gland alveolus development
GO:0060750 IMP epithelial cell proliferation involved in mammary gland duct elongation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076853 AREG amphiregulin protein_coding Danio_rerio
ENSG00000109321 AREG amphiregulin protein_coding Homo_sapiens

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