C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, AMP-activated, beta 1 non-catalytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029513 Prkab1 10090 - 5:116013586-116024508 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031486 Prkab1-001 116013586-116024462 protein_coding
  ENSMUST00000111999 Prkab1-002 116014641-116024508 protein_coding
  ENSMUST00000133098 Prkab1-006 116014435-116024356 nonsense_mediated_decay
  ENSMUST00000141018 Prkab1-007 116019707-116021646 retained_intron
  ENSMUST00000143146 Prkab1-009 116014167-116015161 retained_intron
  ENSMUST00000143524 Prkab1-008 116014316-116018211 retained_intron
  ENSMUST00000147343 Prkab1-005 116017815-116024397 retained_intron
  ENSMUST00000148208 Prkab1-004 116014650-116024451 nonsense_mediated_decay
  ENSMUST00000152174 Prkab1-003 116023899-116024459 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031486ENSMUST00000111999ENSMUST00000143146ENSMUST00000143524ENSMUST00000147343ENSMUST00000148208ENSMUST00000152174
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031486 8.714±1.45 21.341±3.54 15.382±0.68 9.497±1.71 16.492±8.35 40.383±7.05 7.255±4.70 10.306±3.87 22.884±21.11 14.441±3.12 1.933±1.08 11.330±1.71 7.963±3.38 0.628±0.37
ENSMUST00000111999 N/A N/A 18.044±4.84 9.414±0.00 N/A 33.868±0.00 N/A N/A 18.252±4.66 N/A N/A N/A N/A N/A
ENSMUST00000143146 N/A N/A N/A 8.946±0.00 N/A 25.453±1.22 N/A N/A N/A N/A N/A 12.636±2.26 17.781±1.66 0.529±0.00
ENSMUST00000143524 N/A 14.170±0.00 N/A N/A N/A 38.701±7.73 N/A N/A N/A N/A N/A 12.096±0.32 N/A N/A
ENSMUST00000147343 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.862±0.00 N/A N/A
ENSMUST00000148208 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.364±1.37 N/A N/A
ENSMUST00000152174 N/A 73.413±12.63 N/A N/A N/A N/A N/A N/A 12.632±0.00 N/A N/A 20.472±1.85 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004679 TAS AMP-activated protein kinase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0006633 IEA fatty acid biosynthetic process
GO:0010628 IEA positive regulation of gene expression
GO:0019901 IEA protein kinase binding
GO:0031588 IEA AMP-activated protein kinase complex
GO:0043234 IEA protein complex
GO:0050790 IEA regulation of catalytic activity
GO:0051291 IEA protein heterooligomerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044183 prkab1a protein kinase, AMP-activated, beta 1 non-catalytic subunit, a protein_coding Danio_rerio
ENSDARG00000046143 prkab1b protein kinase, AMP-activated, beta 1 non-catalytic subunit, b protein_coding Danio_rerio
ENSG00000111725 PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit protein_coding Homo_sapiens

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