C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, AMP-activated, beta 1 non-catalytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111725 PRKAB1 9606 + 12:119667753-119681630 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000229328 PRKAB1-001 119667753-119681630 protein_coding
  ENST00000537057 PRKAB1-004 119680078-119681587 processed_transcript
  ENST00000537400 PRKAB1-007 119668150-119672427 nonsense_mediated_decay
  ENST00000538271 PRKAB1-009 119678985-119679981 retained_intron
  ENST00000540121 PRKAB1-005 119669424-119680841 protein_coding
  ENST00000541640 PRKAB1-002 119667864-119681624 protein_coding
  ENST00000542698 PRKAB1-003 119677355-119681619 retained_intron
  ENST00000545223 PRKAB1-006 119672244-119679951 protein_coding
  ENST00000545870 PRKAB1-008 119673810-119680001 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000229328ENST00000537057ENST00000540121ENST00000541640ENST00000542698ENST00000545223ENST00000545870
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000229328 20.722±0.00 9.013±0.00 2.750±0.00 6.859±4.81 3.876±2.17 4.990±2.96 1.552±1.35 19.155±0.00 1.046±0.48 4.758±3.10 0.764±0.54 9.127±5.90 16.653±5.13 15.201±0.00
ENST00000537057 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 18.178±0.00 14.822±0.00 20.751±0.00
ENST00000540121 N/A N/A N/A N/A N/A N/A N/A 0.404±0.00 N/A N/A N/A N/A N/A N/A
ENST00000541640 N/A 3.248±0.00 N/A N/A 1.296±0.00 3.497±0.00 N/A 13.457±0.00 N/A 6.402±0.00 3.020±0.00 3.370±0.08 6.444±3.25 5.817±0.00
ENST00000542698 N/A 2.100±0.00 1.129±0.00 1.196±0.00 0.715±0.16 1.925±0.00 0.065±0.00 3.102±0.00 0.241±0.00 0.719±0.00 N/A 1.633±0.32 N/A N/A
ENST00000545223 N/A N/A 10.452±0.00 N/A N/A 5.121±0.00 0.600±0.00 N/A 1.146±0.00 N/A N/A N/A N/A N/A
ENST00000545870 N/A N/A N/A N/A 4.122±0.00 N/A N/A 1.459±0.00 1.611±0.00 N/A 0.884±0.00 5.415±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007G8 CIL_0007G8_0002 CGP 12:119593459-119681630

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IDA protein kinase activity
GO:0004679 IEA AMP-activated protein kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006468 IDA protein phosphorylation
GO:0006633 IEA fatty acid biosynthetic process
GO:0007050 TAS cell cycle arrest
GO:0007165 TAS signal transduction
GO:0008286 TAS insulin receptor signaling pathway
GO:0010628 IDA positive regulation of gene expression
GO:0019901 IEA protein kinase binding
GO:0031588 IEA AMP-activated protein kinase complex
GO:0043234 IEA protein complex
GO:0050790 IEA regulation of catalytic activity
GO:0051291 IEA protein heterooligomerization
GO:0061024 TAS membrane organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044183 prkab1a protein kinase, AMP-activated, beta 1 non-catalytic subunit, a protein_coding Danio_rerio
ENSDARG00000046143 prkab1b protein kinase, AMP-activated, beta 1 non-catalytic subunit, b protein_coding Danio_rerio
ENSMUSG00000029513 Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit protein_coding Mus_musculus

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