C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Eph receptor B4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029710 Ephb4 10090 + 5:137350109-137378669 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000061244 Ephb4-001 137350109-137374528 protein_coding
  ENSMUST00000111054 Ephb4-003 137350513-137374532 protein_coding
  ENSMUST00000111055 Ephb4-002 137350172-137374520 protein_coding
  ENSMUST00000144296 Ephb4-004 137350141-137378669 nonsense_mediated_decay
  ENSMUST00000166239 Ephb4-201 137350430-137374310 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000061244ENSMUST00000111054ENSMUST00000111055ENSMUST00000144296ENSMUST00000166239
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000061244 20.150±6.57 19.582±4.65 11.742±1.25 3.705±1.95 15.276±4.70 33.602±2.65 9.937±0.56 18.561±3.71 6.547±1.82 46.178±14.49 3.725±0.79 23.144±8.77 12.320±5.60
ENSMUST00000111054 N/A N/A N/A N/A 8.272±0.00 N/A N/A N/A N/A N/A N/A 9.359±0.37 N/A
ENSMUST00000111055 N/A N/A 1.552±0.00 N/A N/A N/A N/A N/A N/A N/A 0.591±0.11 5.619±0.00 2.711±0.00
ENSMUST00000144296 N/A 7.551±3.13 N/A N/A 2.468±0.07 N/A N/A N/A 1.408±0.00 N/A N/A 8.362±3.36 N/A
ENSMUST00000166239 9.067±1.12 N/A 2.747±0.00 1.960±0.85 7.119±2.27 N/A 5.877±1.44 5.772±0.61 2.001±0.80 15.999±0.00 1.003±0.26 6.608±1.95 5.074±0.31

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0002042 ISS cell migration involved in sprouting angiogenesis
GO:0003007 IMP heart morphogenesis
GO:0004714 ISS transmembrane receptor protein tyrosine kinase activity
GO:0005003 ISS ephrin receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005887 ISS integral component of plasma membrane
GO:0007155 ISS cell adhesion
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0046777 ISS protein autophosphorylation
GO:0048013 IGI ephrin receptor signaling pathway
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027112 ephb4b eph receptor B4b protein_coding Danio_rerio
ENSDARG00000040346 ephb4a eph receptor B4a protein_coding Danio_rerio
ENSG00000196411 EPHB4 EPH receptor B4 protein_coding Homo_sapiens

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