C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: distal-less homeobox 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029755 Dlx5 10090 - 6:6877805-6882085 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000052609 Dlx5-001 6877805-6882085 protein_coding
  ENSMUST00000142635 Dlx5-002 6877805-6882068 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000052609ENSMUST00000142635
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000052609 2.381±1.58 0.122±0.06 0.019±0.00 3.758±2.09 0.127±0.04 0.042±0.01 N/A N/A 0.029±0.00 0.019±0.00 N/A 0.988±0.46 0.069±0.00 1.251±0.01
ENSMUST00000142635 0.698±0.64 0.024±0.02 0.014±0.00 1.427±0.57 0.110±0.03 0.046±0.00 0.046±0.01 0.019±0.00 0.028±0.02 N/A 0.078±0.02 0.841±0.56 0.048±0.01 0.894±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008VC CIL_0008VC_0002 VISTA 6:6561655-7162377
CIL_0005LA CIL_0005LA_0003 CGP 6:6863334-6882085
CIL_00053E CIL_00053E_0002 CGP 6:6877805-7042979

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001649 IDA osteoblast differentiation
GO:0001958 IMP endochondral ossification
GO:0003677 IDA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0007409 IMP axonogenesis
GO:0007411 IMP axon guidance
GO:0008283 ISS cell proliferation
GO:0030326 IGI embryonic limb morphogenesis
GO:0030509 IMP BMP signaling pathway
GO:0030855 IGI epithelial cell differentiation
GO:0042472 IMP inner ear morphogenesis
GO:0043583 IMP ear development
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048646 IGI anatomical structure formation involved in morphogenesis
GO:0050679 IGI positive regulation of epithelial cell proliferation
GO:0060021 IMP palate development
GO:0060166 IMP olfactory pit development
GO:0060322 IGI head development
GO:0060325 IMP face morphogenesis
GO:0060349 IMP bone morphogenesis
GO:0071773 IMP cellular response to BMP stimulus
GO:0071837 IPI HMG box domain binding
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway
GO:1901522 IMP positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042296 dlx5a distal-less homeobox gene 5a protein_coding Danio_rerio
ENSG00000105880 DLX5 distal-less homeobox 5 protein_coding Homo_sapiens

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