C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MAD2 mitotic arrest deficient-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029910 Mad2l1 10090 + 6:66535390-66541033 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000101343 Mad2l1-002 66535468-66540991 protein_coding
  ENSMUST00000116605 Mad2l1-001 66535390-66541033 protein_coding
  ENSMUST00000125430 Mad2l1-003 66535425-66541020 retained_intron
  ENSMUST00000135411 Mad2l1-004 66535678-66536073 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000101343ENSMUST00000116605ENSMUST00000125430
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000101343 1.835±1.16 N/A 0.691±0.25 3.775±1.42 0.477±0.17 1.397±0.40 0.313±0.11 N/A 9.246±6.91 0.475±0.00 0.214±0.06 3.713±1.20 5.774±3.38 0.173±0.00
ENSMUST00000116605 6.333±4.54 2.383±0.54 3.511±0.58 7.486±5.98 2.895±1.17 6.385±1.67 1.229±0.27 2.443±0.49 21.503±22.61 3.119±0.10 0.512±0.22 7.061±2.95 16.066±13.09 6.444±2.52
ENSMUST00000125430 N/A 0.338±0.21 N/A 1.941±0.00 0.516±0.08 0.730±0.20 0.139±0.00 N/A 4.475±0.00 0.357±0.02 0.139±0.00 1.000±0.28 N/A 1.025±0.17

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000070 IMP mitotic sister chromatid segregation
GO:0000775 IDA chromosome, centromeric region
GO:0000776 IDA kinetochore
GO:0000922 IDA spindle pole
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005643 IEA nuclear pore
GO:0005829 ISS cytosol
GO:0007093 IEA mitotic cell cycle checkpoint
GO:0007094 ISA mitotic spindle assembly checkpoint
GO:0042177 ISS negative regulation of protein catabolic process
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043066 IMP negative regulation of apoptotic process
GO:0045841 TAS negative regulation of mitotic metaphase/anaphase transition
GO:0045930 IEA negative regulation of mitotic cell cycle
GO:0048471 ISS perinuclear region of cytoplasm
GO:0060564 IEA negative regulation of mitotic anaphase-promoting complex activity
GO:0072686 ISS mitotic spindle
GO:0090267 IMP positive regulation of mitotic cell cycle spindle assembly checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004713 mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) protein_coding Danio_rerio
ENSG00000164109 MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) protein_coding Homo_sapiens

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