C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium/calmodulin-dependent protein kinase I
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030272 Camk1 10090 - 6:113334124-113343984 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032409 Camk1-001 113334124-113343984 protein_coding
  ENSMUST00000149497 Camk1-005 113334137-113343904 retained_intron
  ENSMUST00000153067 Camk1-006 113334128-113336621 retained_intron
  ENSMUST00000155543 Camk1-007 113338123-113343978 protein_coding
  ENSMUST00000156512 Camk1-004 113334128-113340917 retained_intron
  ENSMUST00000156853 Camk1-003 113340903-113343963 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032409ENSMUST00000149497ENSMUST00000153067ENSMUST00000155543ENSMUST00000156512
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032409 60.276±9.99 53.361±11.20 45.495±6.43 32.604±10.95 35.842±7.18 33.266±2.92 42.403±3.44 34.437±4.03 9.422±1.54 53.665±7.76 17.594±1.65 43.725±11.43 22.237±12.53 N/A
ENSMUST00000149497 N/A N/A N/A 46.630±0.00 N/A N/A N/A N/A N/A N/A N/A 27.214±15.05 11.646±0.83 1.563±0.00
ENSMUST00000153067 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.542±0.00 N/A N/A
ENSMUST00000155543 N/A 32.337±1.62 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000156512 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.785±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002WL CIL_0002WL_0002 CGP 6:113307181-113335068
CIL_000243 CIL_000243_0002 CGP 6:113326972-113343984
CIL_0002WT CIL_0002WT_0002 CGP 6:113334124-113377883

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004683 ISS calmodulin-dependent protein kinase activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005954 TAS calcium- and calmodulin-dependent protein kinase complex
GO:0006468 IDA protein phosphorylation
GO:0006913 IDA nucleocytoplasmic transport
GO:0007049 IEA cell cycle
GO:0007165 IDA signal transduction
GO:0010976 ISS positive regulation of neuron projection development
GO:0032880 ISS regulation of protein localization
GO:0043393 ISS regulation of protein binding
GO:0046827 IDA positive regulation of protein export from nucleus
GO:0051147 ISS regulation of muscle cell differentiation
GO:0051149 IEA positive regulation of muscle cell differentiation
GO:0051835 ISS positive regulation of synapse structural plasticity
GO:0060999 ISS positive regulation of dendritic spine development
GO:0071902 ISS positive regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029474 BX571768.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000060116 CAMK1 (2 of 2) calcium/calmodulin-dependent protein kinase I protein_coding Danio_rerio
ENSG00000134072 CAMK1 calcium/calmodulin-dependent protein kinase I protein_coding Homo_sapiens

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