C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CREB regulated transcription coactivator 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030527 Crtc3 10090 - 7:80586627-80688877 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000122255 Crtc3-001 80586627-80688877 protein_coding
  ENSMUST00000127182 Crtc3-005 80595720-80599136 retained_intron
  ENSMUST00000127326 Crtc3-004 80595782-80629626 nonsense_mediated_decay
  ENSMUST00000149176 Crtc3-006 80592829-80609932 nonsense_mediated_decay
  ENSMUST00000152668 Crtc3-002 80673270-80688877 retained_intron
  ENSMUST00000154761 Crtc3-003 80618107-80629707 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000122255
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000122255 7.807±2.01 8.342±3.87 6.199±0.42 2.476±1.70 3.799±2.78 2.224±0.76 3.115±0.38 3.561±0.58 1.977±1.05 7.762±2.67 2.541±0.63 5.880±2.21 6.062±3.53 2.561±1.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008AY CIL_0008AY_0002 VISTA 7:80145068-80746500
CIL_0008FE CIL_0008FE_0002 VISTA 7:80488938-81090184
CIL_00073S CIL_00073S_0002 CGP 7:80586627-80803331

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0008140 IEA cAMP response element binding protein binding
GO:0032793 IEA positive regulation of CREB transcription factor activity
GO:0043951 IDA negative regulation of cAMP-mediated signaling
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050995 IMP negative regulation of lipid catabolic process
GO:0051289 IEA protein homotetramerization
GO:0097009 IMP energy homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052114 crtc3 CREB regulated transcription coactivator 3 protein_coding Danio_rerio
ENSG00000140577 CRTC3 CREB regulated transcription coactivator 3 protein_coding Homo_sapiens

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