C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cathepsin C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030560 Ctsc 10090 + 7:88278085-88310888 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032779 Ctsc-001 88278085-88310888 protein_coding
  ENSMUST00000128791 Ctsc-004 88278134-88308023 protein_coding
  ENSMUST00000131108 Ctsc-002 88278138-88291390 retained_intron
  ENSMUST00000139159 Ctsc-003 88278138-88281783 retained_intron
  ENSMUST00000152834 Ctsc-005 88296852-88302300 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032779ENSMUST00000128791ENSMUST00000131108ENSMUST00000139159
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032779 10.914±1.01 4.668±0.52 10.891±0.59 0.976±0.42 16.025±3.24 6.752±1.72 5.295±1.19 3.040±0.94 13.008±3.29 30.938±3.60 4.731±0.78 8.640±3.29 7.113±8.23 0.764±0.21
ENSMUST00000128791 N/A N/A N/A 1.948±0.00 N/A N/A N/A N/A N/A N/A N/A 12.096±0.00 3.685±0.75 N/A
ENSMUST00000131108 5.852±0.85 N/A 4.865±0.37 0.338±0.12 6.483±0.42 N/A 1.505±0.22 0.953±0.30 3.526±1.04 11.592±1.19 3.639±0.47 3.676±1.21 1.697±1.67 0.180±0.09
ENSMUST00000139159 30.992±1.08 51.020±11.41 N/A N/A 98.443±53.30 49.292±10.13 N/A 5.657±0.57 28.841±7.54 118.049±44.64 N/A 49.026±16.58 N/A 1.039±0.11

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001913 IGI T cell mediated cytotoxicity
GO:0004252 IMP serine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005764 IEA lysosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0006508 IMP proteolysis
GO:0006915 IGI apoptotic process
GO:0007568 IEA aging
GO:0008234 IEA cysteine-type peptidase activity
GO:0010033 IEA response to organic substance
GO:0016020 IEA membrane
GO:0016505 IGI peptidase activator activity involved in apoptotic process
GO:0019902 IEA phosphatase binding
GO:0031404 IEA chloride ion binding
GO:0042802 IEA identical protein binding
GO:0043621 IEA protein self-association
GO:0051087 IEA chaperone binding
GO:0070062 IEA extracellular vesicular exosome
GO:1903052 IEA positive regulation of proteolysis involved in cellular protein catabolic process
GO:2001235 IGI positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018806 ctsc cathepsin C protein_coding Danio_rerio
ENSG00000109861 CTSC cathepsin C protein_coding Homo_sapiens

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