C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cathepsin C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109861 CTSC 9606 - 11:88293592-88337787 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000227266 CTSC-001 88293592-88337787 protein_coding
  ENST00000393301 CTSC-008 88326365-88337700 processed_transcript
  ENST00000524463 CTSC-002 88320811-88337761 protein_coding
  ENST00000527018 CTSC-004 88296159-88337749 protein_coding
  ENST00000528020 CTSC-009 88326086-88328198 protein_coding
  ENST00000529974 CTSC-003 88326117-88337733 protein_coding
  ENST00000533865 CTSC-005 88309284-88337740 processed_transcript
  ENST00000533897 CTSC-010 88293788-88299755 retained_intron
  ENST00000534131 CTSC-007 88334736-88337736 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000227266ENST00000524463ENST00000533897
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000227266 14.204±0.00 33.728±0.00 9.895±0.00 5.926±0.00 17.432±3.73 16.003±2.14 5.958±4.95 38.302±34.13 14.167±0.35 57.038±14.17 3.600±2.42 13.420±4.35 107.592±23.95 14.088±0.00
ENST00000524463 1.131±0.00 2.629±0.00 0.787±0.00 0.506±0.41 1.408±0.12 1.838±0.28 0.299±0.18 0.319±0.00 0.925±0.00 N/A 0.396±0.00 1.054±0.02 N/A 0.983±0.51
ENST00000533897 N/A N/A N/A N/A 1.827±0.00 1.549±0.00 0.231±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001JD CIL_0001JD_0002 CGP 11:88113242-88337787
CIL_0001JJ CIL_0001JJ_0002 CGP 11:88293592-89065945

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001913 IEA T cell mediated cytotoxicity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005764 ISS lysosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0006508 IDA:IEA proteolysis
GO:0006915 IEA apoptotic process
GO:0006955 TAS immune response
GO:0007568 IEA aging
GO:0008234 IDA:IEA cysteine-type peptidase activity
GO:0010033 IEA response to organic substance
GO:0016020 IDA membrane
GO:0016505 IEA peptidase activator activity involved in apoptotic process
GO:0019902 ISS phosphatase binding
GO:0031404 IEA chloride ion binding
GO:0042802 IEA identical protein binding
GO:0043621 IEA protein self-association
GO:0051087 ISS chaperone binding
GO:0070062 IDA extracellular vesicular exosome
GO:1903052 ISS positive regulation of proteolysis involved in cellular protein catabolic process
GO:2001235 IEA positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018806 ctsc cathepsin C protein_coding Danio_rerio
ENSMUSG00000030560 Ctsc cathepsin C protein_coding Mus_musculus

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