C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: progesterone receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031870 Pgr 10090 + 9:8899833-8968611 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000070463 Pgr-001 8900468-8965425 protein_coding
  ENSMUST00000098986 Pgr-002 8900468-8965425 protein_coding
  ENSMUST00000151080 Pgr-003 8900419-8948607 retained_intron
  ENSMUST00000189181 Pgr-201 8899833-8968611 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000070463ENSMUST00000151080ENSMUST00000189181
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000070463 11.120±11.04 0.134±0.05 N/A 0.655±0.00 6.798±2.85 0.031±0.02 0.034±0.01 0.174±0.12 0.005±0.00 0.364±0.06 10.052±3.11 N/A 0.010±0.00
ENSMUST00000151080 8.990±6.33 0.042±0.00 0.029±0.00 N/A 5.287±3.16 0.006±0.00 N/A 0.050±0.02 N/A 0.318±0.08 6.535±5.81 0.088±0.07 N/A
ENSMUST00000189181 7.964±7.93 0.023±0.00 0.130±0.01 0.391±0.32 2.037±0.53 N/A 0.004±0.00 0.081±0.03 0.004±0.00 0.384±0.08 2.215±1.01 0.246±0.21 0.010±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003T4 CIL_0003T4_0002 CGP 9:8544196-8968611

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001542 IMP ovulation from ovarian follicle
GO:0002070 IMP epithelial cell maturation
GO:0003707 IDA steroid hormone receptor activity
GO:0004879 IMP ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005102 IEA receptor binding
GO:0005496 IEA steroid binding
GO:0005515 IEA protein binding
GO:0005634 IC nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0010629 IEA negative regulation of gene expression
GO:0019899 IEA enzyme binding
GO:0030879 IMP mammary gland development
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050678 IMP regulation of epithelial cell proliferation
GO:0050847 IDA progesterone receptor signaling pathway
GO:0060748 IMP tertiary branching involved in mammary gland duct morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035966 pgr progesterone receptor protein_coding Danio_rerio
ENSG00000082175 PGR progesterone receptor protein_coding Homo_sapiens

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