C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TNFRSF1A-associated via death domain
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031887 Tradd 10090 - 8:105258286-105264609 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034359 Tradd-001 105258286-105264609 protein_coding
  ENSMUST00000136239 Tradd-004 105259190-105260120 retained_intron
  ENSMUST00000144762 Tradd-003 105259283-105264581 nonsense_mediated_decay
  ENSMUST00000147670 Tradd-002 105259757-105264603 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034359ENSMUST00000136239ENSMUST00000144762ENSMUST00000147670
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034359 5.995±2.00 11.620±1.25 5.400±2.01 1.632±0.76 7.485±2.26 45.491±5.58 1.310±0.29 5.464±0.90 4.665±1.97 6.342±1.60 0.895±0.40 8.653±1.82 7.813±1.67 0.984±0.21
ENSMUST00000136239 N/A 4.336±0.36 N/A N/A 4.194±1.67 19.024±0.00 N/A N/A N/A N/A 0.477±0.00 5.890±3.78 5.474±0.00 N/A
ENSMUST00000144762 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.708±0.00
ENSMUST00000147670 N/A N/A N/A 1.120±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005T5 CIL_0005T5_0002 CGP 8:105252638-105264609
CIL_0005T4 CIL_0005T4_0002 CGP 8:105258286-105269326

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004871 IEA signal transducer activity
GO:0005164 IEA tumor necrosis factor receptor binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006915 RCA apoptotic process
GO:0019900 IEA kinase binding
GO:0032403 IEA protein complex binding
GO:0042802 IEA identical protein binding
GO:0042981 RCA regulation of apoptotic process
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043234 IEA protein complex
GO:0043235 IEA receptor complex
GO:0045121 IEA membrane raft
GO:0051291 IEA protein heterooligomerization
GO:0051798 IMP positive regulation of hair follicle development
GO:0060090 IEA binding, bridging
GO:0070513 IEA death domain binding
GO:0097191 IGI extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036057 tradd tnfrsf1a-associated via death domain protein_coding Danio_rerio
ENSG00000102871 TRADD TNFRSF1A-associated via death domain protein_coding Homo_sapiens

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