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__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
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DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
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DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
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DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
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Institute of Cardiovascular Regeneration Webtool Repository
C-It-Loci: A knowledge database for tissue-enriched loci.
Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main
Expression Patterns
Heat Map
Numeric Values
Transcript ';
Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis ENSMUST00000063278
Transcript ID
Adipose
Adrenal
Bladder
Brain
Breast
Colon
Heart
Kidney
Liver
Lung
Muscle
Ovary
Placenta
Testis
ENSMUST00000063278
46.499±34.59
8.119±0.97
0.671±0.13
5.352±5.33
10.118±3.16
20.471±2.11
3.196±0.35
38.757±7.55
389.370±269.51
1.977±0.62
3.869±0.87
72.047±18.06
9.960±8.42
64.386±35.51
Conserved Regions
Region ID Sub-Region Region Type Position
CIL_0008A0
CIL_0008A0_0002
VISTA
8:123980149-124582109
CIL_0007WK
CIL_0007WK_0002
VISTA
8:124343702-124945898
CIL_000610
CIL_000610_0002
CGP
8:124520767-124569706
CIL_000615
CIL_000615_0002
CGP
8:124556534-124618731
Gene Ontology
GO ID Evidence Type GO Description
GO:0001543
IMP
ovarian follicle rupture
GO:0001568
IMP
blood vessel development
GO:0001658
IDA
branching involved in ureteric bud morphogenesis
GO:0001822
IMP
kidney development
GO:0001991
IMP
regulation of systemic arterial blood pressure by circulatory renin-angiotensin
GO:0001998
IDA
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
GO:0001999
IMP
renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure
GO:0002018
IMP
renin-angiotensin regulation of aldosterone production
GO:0002019
IMP
regulation of renal output by angiotensin
GO:0002035
IDA
brain renin-angiotensin system
GO:0003014
IEA
renal system process
GO:0003051
IEA
angiotensin-mediated drinking behavior
GO:0003331
IEA
positive regulation of extracellular matrix constituent secretion
GO:0004867
IBA
serine-type endopeptidase inhibitor activity
GO:0005179
IEA
hormone activity
GO:0005515
IEA
protein binding
GO:0005615
IDA
extracellular space
GO:0005737
IEA
cytoplasm
GO:0006883
IEA
cellular sodium ion homeostasis
GO:0007160
IMP
cell-matrix adhesion
GO:0007166
IEA
cell surface receptor signaling pathway
GO:0007186
IEA
G-protein coupled receptor signaling pathway
GO:0007202
IEA
activation of phospholipase C activity
GO:0007250
IDA
activation of NF-kappaB-inducing kinase activity
GO:0007565
IEA
female pregnancy
GO:0007568
IEA
aging
GO:0007588
IMP
excretion
GO:0008065
IMP
establishment of blood-nerve barrier
GO:0008217
IMP
regulation of blood pressure
GO:0008284
IEA
positive regulation of cell proliferation
GO:0008285
IMP
negative regulation of cell proliferation
GO:0009409
IMP
response to cold
GO:0009651
IMP
response to salt stress
GO:0010468
IDA
regulation of gene expression
GO:0010535
IEA
positive regulation of activation of JAK2 kinase activity
GO:0010595
IEA
positive regulation of endothelial cell migration
GO:0010613
IEA
positive regulation of cardiac muscle hypertrophy
GO:0010628
IDA
positive regulation of gene expression
GO:0010873
IEA
positive regulation of cholesterol esterification
GO:0010951
IBA
negative regulation of endopeptidase activity
GO:0014061
IEA
regulation of norepinephrine secretion
GO:0014068
IEA
positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014824
IEA
artery smooth muscle contraction
GO:0014873
IEA
response to muscle activity involved in regulation of muscle adaptation
GO:0016525
IEA
negative regulation of angiogenesis
GO:0030162
IBA
regulation of proteolysis
GO:0030198
IMP
extracellular matrix organization
GO:0030308
IEA
negative regulation of cell growth
GO:0030432
IMP
peristalsis
GO:0031701
IEA
angiotensin receptor binding
GO:0031702
IDA
type 1 angiotensin receptor binding
GO:0031703
IPI
type 2 angiotensin receptor binding
GO:0032270
IEA
positive regulation of cellular protein metabolic process
GO:0032930
IEA
positive regulation of superoxide anion generation
GO:0033138
IDA
positive regulation of peptidyl-serine phosphorylation
GO:0034104
IEA
negative regulation of tissue remodeling
GO:0035411
IEA
catenin import into nucleus
GO:0035813
IEA
regulation of renal sodium excretion
GO:0035815
IEA
positive regulation of renal sodium excretion
GO:0040018
IMP
positive regulation of multicellular organism growth
GO:0042310
IEA
vasoconstriction
GO:0042311
IEA
vasodilation
GO:0042445
IMP
hormone metabolic process
GO:0042756
IMP
drinking behavior
GO:0042981
IDA
regulation of apoptotic process
GO:0043085
IEA
positive regulation of catalytic activity
GO:0043410
IMP
positive regulation of MAPK cascade
GO:0043524
IMP
negative regulation of neuron apoptotic process
GO:0045429
IEA
positive regulation of nitric oxide biosynthetic process
GO:0045723
IMP
positive regulation of fatty acid biosynthetic process
GO:0045742
IEA
positive regulation of epidermal growth factor receptor signaling pathway
GO:0045777
IEA
positive regulation of blood pressure
GO:0045893
IEA
positive regulation of transcription, DNA-templated
GO:0045909
IEA
positive regulation of vasodilation
GO:0046622
IMP
positive regulation of organ growth
GO:0048143
IMP
astrocyte activation
GO:0048144
IEA
fibroblast proliferation
GO:0048146
IEA
positive regulation of fibroblast proliferation
GO:0048169
IEA
regulation of long-term neuronal synaptic plasticity
GO:0048659
IDA
smooth muscle cell proliferation
GO:0050663
IEA
cytokine secretion
GO:0050727
IDA
regulation of inflammatory response
GO:0050731
IEA
positive regulation of peptidyl-tyrosine phosphorylation
GO:0051145
IDA
smooth muscle cell differentiation
GO:0051387
IEA
negative regulation of neurotrophin TRK receptor signaling pathway
GO:0051403
IEA
stress-activated MAPK cascade
GO:0051924
IEA
regulation of calcium ion transport
GO:0051969
IEA
regulation of transmission of nerve impulse
GO:0061049
IEA
cell growth involved in cardiac muscle cell development
GO:0061098
IEA
positive regulation of protein tyrosine kinase activity
GO:0070062
IEA
extracellular vesicular exosome
GO:0070371
IEA
ERK1 and ERK2 cascade
GO:0070471
IEA
uterine smooth muscle contraction
GO:0071260
IEA
cellular response to mechanical stimulus
GO:0072562
IEA
blood microparticle
GO:0090190
IEA
positive regulation of branching involved in ureteric bud morphogenesis
GO:1900020
IDA
positive regulation of protein kinase C activity
GO:2001238
IEA
positive regulation of extrinsic apoptotic signaling pathway
Homologs
ENSEMBL Accession
Gene Name
Description
Biotype
Species
ENSDARG00000016412
agt
angiotensinogen
protein_coding
Danio_rerio
ENSG00000135744
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
protein_coding
Homo_sapiens
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'FormHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/FormHelper.php',
'SessionHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/SessionHelper.php'
)
$config = '_cake_core_'
$settings = array(
'prefix' => '*****',
'engine' => 'File',
'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
'serialize' => true,
'duration' => (int) 10,
'lock' => true,
'isWindows' => false,
'mask' => (int) 436,
'probability' => (int) 100,
'groups' => array()
)
$success = false Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ?? Warning (512) : _cake_core_ cache was unable to write 'method_cache' to File cache [CORE/Cake/Cache/Cache.php , line 323 ]Code Context ),
E_USER_WARNING
); $key = 'method_cache'
$value = array(
(int) 0 => false,
'name' => array(
'45b989c52610ac6d773f6b83d6108190' => '`citloci`',
'4d0d73f550e4b0573d9cf666d63a0244' => '`genes`',
'003d5968b53baeeb0cb27d56c4d447af' => '`Gene`.`id`',
'f32f1dc049466870a2299961f0604112' => '`Gene`.`gene_version`',
'433a39b330b04a021541e6fa89d80ffd' => '`Gene`.`tax_id`',
'56705ff3488da428f13156180dbc9fbc' => '`Gene`.`assembly`',
'b7d572bb36c8f0f2ecfe36921c14fbf3' => '`Gene`.`chromosome`',
'edf6b12f8a40424f91fa0a40f0eab275' => '`Gene`.`strand`',
'71d92ec0ad29837870abd0de3ae8addc' => '`Gene`.`start`',
'62e43d606bf4cdae2d6694c62e19e7fa' => '`Gene`.`end`',
'7043386674301bd31c5e629dfdadabd4' => '`Gene`.`gene_name`',
'f1454297621ddcf07c418e47f67d3857' => '`Gene`.`gene_source`',
'27d53785bfcd771f1901030b4bb87d02' => '`Gene`.`gene_biotype`',
'b93574bf8a03f2d6f6486e920115e0d1' => '`Gene`.`annotation_version`',
'1c4a3f5d90070e8ea1c62ca077df603e' => '`Gene`.`gene_description`',
'8ca7a0c53312b8ae3cfa40a9d814adac' => '`Gene`'
),
'fields' => array(
'0ea8c82680a14e2566476c4ab527af47' => array(
(int) 0 => '`Gene`.`id`',
(int) 1 => '`Gene`.`gene_version`',
(int) 2 => '`Gene`.`tax_id`',
(int) 3 => '`Gene`.`assembly`',
(int) 4 => '`Gene`.`chromosome`',
(int) 5 => '`Gene`.`strand`',
(int) 6 => '`Gene`.`start`',
(int) 7 => '`Gene`.`end`',
(int) 8 => '`Gene`.`gene_name`',
(int) 9 => '`Gene`.`gene_source`',
(int) 10 => '`Gene`.`gene_biotype`',
(int) 11 => '`Gene`.`annotation_version`',
(int) 12 => '`Gene`.`gene_description`'
)
)
)
$config = '_cake_core_'
$settings = array(
'prefix' => '*****',
'engine' => 'File',
'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
'serialize' => true,
'duration' => (int) 10,
'lock' => true,
'isWindows' => false,
'mask' => (int) 436,
'probability' => (int) 100,
'groups' => array()
)
$success = false Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??