C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031994 Adamts8 10090 + 9:30942562-30963838 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000068135 Adamts8-001 30942562-30962856 protein_coding
  ENSMUST00000163037 Adamts8-002 30943458-30963838 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000068135ENSMUST00000163037
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000068135 0.874±0.76 0.106±0.05 0.970±0.24 0.574±0.13 0.451±0.15 1.081±0.32 1.046±0.57 0.634±0.23 0.036±0.03 1.601±0.38 0.600±0.37 0.607±0.30 0.554±0.25 0.131±0.07
ENSMUST00000163037 0.029±0.00 0.071±0.04 N/A N/A N/A N/A N/A N/A 0.013±0.00 N/A 0.066±0.00 0.092±0.05 0.048±0.00 0.022±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003CQ CIL_0003CQ_0002 CGP 9:30899155-30963838

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IEA proteolysis
GO:0008237 IEA metallopeptidase activity
GO:0008270 IEA zinc ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007709 adamts8a ADAM metallopeptidase with thrombospondin type 1 motif, 8a protein_coding Danio_rerio
ENSDARG00000058252 adamts15b ADAM metallopeptidase with thrombospondin type 1 motif, 15b protein_coding Danio_rerio
ENSG00000134917 ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 protein_coding Homo_sapiens

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