C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: amyloid beta (A4) precursor-like protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031996 Aplp2 10090 - 9:31149557-31211815 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072634 Aplp2-201 31149557-31211815 protein_coding
  ENSMUST00000079758 Aplp2-202 31149557-31211815 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072634ENSMUST00000079758
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072634 250.019±100.56 71.280±21.06 200.827±5.18 30.239±0.86 139.029±28.47 60.187±8.49 71.180±7.72 109.848±20.66 76.860±20.15 152.153±9.45 29.692±1.46 163.409±62.57 90.748±41.19 39.576±3.42
ENSMUST00000079758 63.039±21.38 128.234±38.78 33.907±0.51 45.356±26.70 59.456±11.43 23.959±11.30 25.744±1.28 48.762±19.42 17.522±2.87 45.639±3.14 6.704±0.48 126.638±42.07 19.660±6.12 15.450±1.44

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001967 IGI suckling behavior
GO:0003677 IEA DNA binding
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005886 IEA plasma membrane
GO:0006878 IMP cellular copper ion homeostasis
GO:0007176 IGI regulation of epidermal growth factor-activated receptor activity
GO:0007617 IGI mating behavior
GO:0007626 IGI locomotory behavior
GO:0008201 IEA heparin binding
GO:0008203 IGI cholesterol metabolic process
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030198 IGI extracellular matrix organization
GO:0030900 IGI forebrain development
GO:0030901 IGI midbrain development
GO:0042802 IEA identical protein binding
GO:0043393 IGI regulation of protein binding
GO:0046914 IEA transition metal ion binding
GO:0050885 IGI neuromuscular process controlling balance
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054864 aplp2 amyloid beta (A4) precursor-like protein 2 protein_coding Danio_rerio
ENSG00000084234 APLP2 amyloid beta (A4) precursor-like protein 2 protein_coding Homo_sapiens

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