C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apolipoprotein A-IV
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032080 Apoa4 10090 + 9:46240696-46243459 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034585 Apoa4-001 46240696-46243459 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000034585
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000034585 0.022±0.01 0.159±0.07 0.013±0.00 0.088±0.00 0.445±0.33 0.106±0.04 0.016±0.00 1.885±0.52 42.581±41.66 0.061±0.02 37.661±23.49 281.756±264.32 0.312±0.36

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RC CIL_0007RC_0002 VISTA 9:45818249-46421546
CIL_0008EK CIL_0008EK_0002 VISTA 9:46081147-46681838

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002227 IMP innate immune response in mucosa
GO:0005507 IEA copper ion binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005829 TAS cytosol
GO:0006982 IEA response to lipid hydroperoxide
GO:0007159 IEA leukocyte cell-cell adhesion
GO:0008203 IEA cholesterol metabolic process
GO:0009986 IEA cell surface
GO:0010873 IEA positive regulation of cholesterol esterification
GO:0010898 IEA positive regulation of triglyceride catabolic process
GO:0016209 IEA antioxidant activity
GO:0017127 IEA cholesterol transporter activity
GO:0019430 IEA removal of superoxide radicals
GO:0030300 IMP regulation of intestinal cholesterol absorption
GO:0031210 IEA phosphatidylcholine binding
GO:0032374 IEA regulation of cholesterol transport
GO:0033344 IEA cholesterol efflux
GO:0033700 IEA phospholipid efflux
GO:0034361 IEA very-low-density lipoprotein particle
GO:0034364 IEA high-density lipoprotein particle
GO:0034372 IEA very-low-density lipoprotein particle remodeling
GO:0034445 IEA negative regulation of plasma lipoprotein particle oxidation
GO:0035634 IEP response to stilbenoid
GO:0042157 IEA lipoprotein metabolic process
GO:0042627 IEA chylomicron
GO:0042632 IEA cholesterol homeostasis
GO:0042744 IEA hydrogen peroxide catabolic process
GO:0042803 IEA protein homodimerization activity
GO:0043691 IEA reverse cholesterol transport
GO:0044240 IEA multicellular organismal lipid catabolic process
GO:0045723 IEA positive regulation of fatty acid biosynthetic process
GO:0046470 IEA phosphatidylcholine metabolic process
GO:0051006 IEA positive regulation of lipoprotein lipase activity
GO:0055088 IEA lipid homeostasis
GO:0060228 IEA phosphatidylcholine-sterol O-acyltransferase activator activity
GO:0065005 IEA protein-lipid complex assembly
GO:0070062 IEA extracellular vesicular exosome
GO:0072562 IEA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020866 APOA4 (1 of 4) apolipoprotein A-IV protein_coding Danio_rerio
ENSDARG00000040298 apoa4 apolipoprotein A-IV protein_coding Danio_rerio
ENSDARG00000086281 APOA4 (3 of 4) apolipoprotein A-IV protein_coding Danio_rerio
ENSDARG00000094929 APOA4 (4 of 4) apolipoprotein A-IV protein_coding Danio_rerio
ENSG00000110244 APOA4 apolipoprotein A-IV protein_coding Homo_sapiens

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