C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: c-src tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032312 Csk 10090 - 9:57626647-57645653 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034863 Csk-201 57626647-57645653 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034863
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034863 11.849±3.34 24.893±1.49 15.453±3.25 20.934±10.01 31.926±16.83 24.892±3.42 4.357±1.91 8.848±3.06 13.835±4.52 21.759±1.51 2.300±1.71 16.636±3.47 21.537±9.64 2.060±0.75

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UD CIL_0007UD_0002 VISTA 9:57506610-58107834

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002376 IEA immune system process
GO:0004713 TAS protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 TAS ATP binding
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005911 IDA cell-cell junction
GO:0006468 TAS protein phosphorylation
GO:0007420 IEA brain development
GO:0008285 IGI negative regulation of cell proliferation
GO:0010989 IEA negative regulation of low-density lipoprotein particle clearance
GO:0016740 TAS transferase activity
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019903 IEA protein phosphatase binding
GO:0032715 IEA negative regulation of interleukin-6 production
GO:0033673 IEA negative regulation of kinase activity
GO:0034332 IEA adherens junction organization
GO:0035556 TAS intracellular signal transduction
GO:0042802 IEA identical protein binding
GO:0042997 IEA negative regulation of Golgi to plasma membrane protein transport
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0045121 IEA membrane raft
GO:0045779 IEA negative regulation of bone resorption
GO:0046777 IEA protein autophosphorylation
GO:0048709 IEA oligodendrocyte differentiation
GO:0050765 IEA negative regulation of phagocytosis
GO:0050863 TAS regulation of T cell activation
GO:0060368 IEA regulation of Fc receptor mediated stimulatory signaling pathway
GO:0070062 IEA extracellular vesicular exosome
GO:0070064 IEA proline-rich region binding
GO:0070373 IEA negative regulation of ERK1 and ERK2 cascade
GO:0071375 IEA cellular response to peptide hormone stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067996 CSK (1 of 2) c-src tyrosine kinase protein_coding Danio_rerio
ENSDARG00000070805 csk c-src tyrosine kinase protein_coding Danio_rerio
ENSG00000103653 CSK c-src tyrosine kinase protein_coding Homo_sapiens

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