C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatidylinositol 3-kinase, catalytic, beta polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032462 Pik3cb 10090 - 9:99036654-99140621 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035037 Pik3cb-001 99036654-99140087 protein_coding
  ENSMUST00000124723 Pik3cb-003 99101350-99140621 protein_coding
  ENSMUST00000136965 Pik3cb-002 99038401-99139925 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035037ENSMUST00000136965
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035037 1.564±0.00 0.753±0.01 0.482±0.03 0.514±0.08 1.089±0.17 0.449±0.17 0.305±0.03 0.993±0.24 0.803±0.21 2.405±0.71 0.231±0.05 1.035±0.84 3.112±1.10 0.274±0.08
ENSMUST00000136965 6.585±1.25 2.212±0.91 1.363±0.24 2.330±0.42 5.072±0.72 0.664±0.23 1.539±0.33 3.262±0.52 2.100±1.29 5.776±1.79 1.228±0.06 1.562±0.53 14.993±5.75 1.498±0.51

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001952 IMP regulation of cell-matrix adhesion
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005886 IBA plasma membrane
GO:0005942 IBA phosphatidylinositol 3-kinase complex
GO:0006874 IMP cellular calcium ion homeostasis
GO:0006897 IEA endocytosis
GO:0006914 IEA autophagy
GO:0007156 IMP homophilic cell adhesion via plasma membrane adhesion molecules
GO:0016303 IMP 1-phosphatidylinositol-3-kinase activity
GO:0030168 IMP platelet activation
GO:0035005 IBA 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0036092 IMP phosphatidylinositol-3-phosphate biosynthetic process
GO:0040016 IMP embryonic cleavage
GO:0043560 IPI insulin receptor substrate binding
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0046934 IBA phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048015 IEA phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075253 pik3cb phosphoinositide-3-kinase, catalytic, beta polypeptide protein_coding Danio_rerio
ENSG00000051382 PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta protein_coding Homo_sapiens

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