Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	CD59a antigen
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000032679	Cd59a	10090	+	2:104095801-104115354	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000040423		Cd59a-001	104095801-104115354	protein_coding
	ENSMUST00000153312		Cd59a-002	104095840-104114263	processed_transcript
	ENSMUST00000168176		Cd59a-201	104095801-104115349	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENSMUST00000040423	51.570±34.24	39.666±4.47	55.398±6.08	2.330±0.19	23.539±10.07	7.293±0.93	27.720±4.08	19.787±1.63	30.321±10.35	13.246±1.15	8.088±1.47	13.785±3.73	11.750±6.18	5.012±2.37
ENSMUST00000153312	N/A	N/A	N/A	3.280±0.00	N/A	N/A	N/A	N/A	13.262±3.10	N/A	2.738±0.40	5.543±1.44	10.278±4.02	6.695±2.99

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_000929	CIL_000929_0002	VISTA	2:103593010-104195664

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0001775	IBA	cell activation
GO:0001848	IBA	complement binding
GO:0001971	IMP	negative regulation of activation of membrane attack complex
GO:0005576	IBA	extracellular region
GO:0009897	IDA	external side of plasma membrane
GO:0016525	IMP	negative regulation of angiogenesis
GO:0030948	IMP	negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031225	IEA	anchored component of membrane
GO:0045916	IDA	negative regulation of complement activation
GO:0090272	IDA	negative regulation of fibroblast growth factor production

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSG00000085063	CD59	CD59 molecule, complement regulatory protein	protein_coding	Homo_sapiens

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