C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tribbles homolog 3 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032715 Trib3 10090 - 2:152337422-152344032 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000040312 Trib3-001 152337422-152344032 protein_coding
  ENSMUST00000123145 Trib3-002 152339748-152343988 processed_transcript
  ENSMUST00000124995 Trib3-003 152342938-152343970 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000040312ENSMUST00000123145ENSMUST00000124995
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000040312 2.401±1.35 0.801±0.54 1.060±0.07 0.148±0.06 1.810±0.61 0.313±0.07 0.893±0.31 0.378±0.13 1.434±0.65 1.945±0.34 0.404±0.20 1.178±0.41 3.674±1.01 0.091±0.04
ENSMUST00000123145 N/A 0.600±0.13 N/A N/A N/A 0.164±0.01 N/A 0.242±0.02 N/A N/A 0.292±0.00 0.590±0.18 N/A N/A
ENSMUST00000124995 N/A N/A N/A N/A N/A N/A N/A 0.475±0.00 N/A N/A N/A N/A N/A 0.064±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00096R CIL_00096R_0002 VISTA 2:152099091-152699726

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003714 IDA transcription corepressor activity
GO:0004860 IEA protein kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0006469 IDA negative regulation of protein kinase activity
GO:0010827 IDA regulation of glucose transport
GO:0019899 IPI enzyme binding
GO:0019901 ISS protein kinase binding
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032092 IDA positive regulation of protein binding
GO:0032436 TAS positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032869 IDA cellular response to insulin stimulus
GO:0034976 ISS response to endoplasmic reticulum stress
GO:0043405 ISS regulation of MAP kinase activity
GO:0045599 IMP negative regulation of fat cell differentiation
GO:0045717 IMP negative regulation of fatty acid biosynthetic process
GO:0045732 IC positive regulation of protein catabolic process
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0051443 IDA positive regulation of ubiquitin-protein transferase activity
GO:0055106 IDA ubiquitin-protein transferase regulator activity
GO:0070059 ISS intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016200 trib3 tribbles homolog 3 (Drosophila) protein_coding Danio_rerio
ENSG00000101255 TRIB3 tribbles pseudokinase 3 protein_coding Homo_sapiens

Loading