C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FK506 binding protein 1a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032966 Fkbp1a 10090 + 2:151542483-151561692 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044011 Fkbp1a-001 151542483-151561692 protein_coding
  ENSMUST00000126670 Fkbp1a-009 151542594-151544677 retained_intron
  ENSMUST00000132614 Fkbp1a-007 151545410-151560713 processed_transcript
  ENSMUST00000137597 Fkbp1a-004 151542594-151559620 processed_transcript
  ENSMUST00000142271 Fkbp1a-002 151543899-151561690 protein_coding
  ENSMUST00000142985 Fkbp1a-003 151542585-151560828 processed_transcript
  ENSMUST00000143230 Fkbp1a-005 151542621-151560942 processed_transcript
  ENSMUST00000144171 Fkbp1a-006 151542696-151557475 processed_transcript
  ENSMUST00000148295 Fkbp1a-010 151542615-151559828 retained_intron
  ENSMUST00000148978 Fkbp1a-008 151542737-151560653 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044011ENSMUST00000137597ENSMUST00000142271
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044011 68.412±21.74 44.616±8.64 92.021±14.80 69.729±3.39 44.851±22.89 31.050±4.34 30.724±8.28 28.365±8.87 20.622±15.45 62.602±18.33 47.565±3.84 55.449±14.49 89.740±36.39 47.717±15.03
ENSMUST00000137597 N/A 50.426±8.58 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 40.540±0.00
ENSMUST00000142271 36.782±10.53 16.672±2.37 N/A N/A 41.534±3.81 12.050±0.90 15.724±10.46 23.739±7.03 10.644±0.86 70.361±26.43 N/A N/A N/A 36.185±14.72

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000413 IBA protein peptidyl-prolyl isomerization
GO:0001933 IDA negative regulation of protein phosphorylation
GO:0003007 IMP heart morphogenesis
GO:0003755 IBA peptidyl-prolyl cis-trans isomerase activity
GO:0004871 IEA signal transducer activity
GO:0005160 IEA transforming growth factor beta receptor binding
GO:0005515 IPI protein binding
GO:0005528 IDA FK506 binding
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0006936 IMP muscle contraction
GO:0007183 IEA SMAD protein complex assembly
GO:0008144 IDA drug binding
GO:0010039 IEA response to iron ion
GO:0016020 IDA membrane
GO:0019221 IMP cytokine-mediated signaling pathway
GO:0019855 IBA calcium channel inhibitor activity
GO:0019899 IEA enzyme binding
GO:0030018 IEA Z disc
GO:0030544 IEA Hsp70 protein binding
GO:0031000 IMP response to caffeine
GO:0031398 IEA positive regulation of protein ubiquitination
GO:0032092 IEA positive regulation of protein binding
GO:0032513 IEA negative regulation of protein phosphatase type 2B activity
GO:0032880 IEA regulation of protein localization
GO:0032925 IEA regulation of activin receptor signaling pathway
GO:0033017 IDA sarcoplasmic reticulum membrane
GO:0034713 IEA type I transforming growth factor beta receptor binding
GO:0042098 IMP T cell proliferation
GO:0042803 IDA protein homodimerization activity
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043206 IEA extracellular fibril organization
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043679 IEA axon terminus
GO:0044325 IPI ion channel binding
GO:0046332 IEA SMAD binding
GO:0048185 IEA activin binding
GO:0050776 IEA regulation of immune response
GO:0051209 IDA release of sequestered calcium ion into cytosol
GO:0051280 IBA negative regulation of release of sequestered calcium ion into cytosol
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060314 IMP regulation of ryanodine-sensitive calcium-release channel activity
GO:0060347 IMP heart trabecula formation
GO:0061077 IBA chaperone-mediated protein folding
GO:0070062 IEA extracellular vesicular exosome
GO:1902991 IEA regulation of amyloid precursor protein catabolic process
GO:1990000 IEA amyloid fibril formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000088832 FKBP1A FK506 binding protein 1A, 12kDa protein_coding Homo_sapiens

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