C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FK506 binding protein 1a
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000044011 Fkbp1a-001 ENSMUSG00000032966 10090 + 2:151542483-151561692 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044011
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044011 68.412±21.74 44.616±8.64 92.021±14.80 69.729±3.39 44.851±22.89 31.050±4.34 30.724±8.28 28.365±8.87 20.622±15.45 62.602±18.33 47.565±3.84 55.449±14.49 89.740±36.39 47.717±15.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000413 IBA protein peptidyl-prolyl isomerization
GO:0001933 IDA negative regulation of protein phosphorylation
GO:0003007 IMP heart morphogenesis
GO:0003755 IBA peptidyl-prolyl cis-trans isomerase activity
GO:0004871 IEA signal transducer activity
GO:0005160 IEA transforming growth factor beta receptor binding
GO:0005515 IPI protein binding
GO:0005528 IDA FK506 binding
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0006936 IMP muscle contraction
GO:0007183 IEA SMAD protein complex assembly
GO:0008144 IDA drug binding
GO:0010039 IEA response to iron ion
GO:0016020 IDA membrane
GO:0019221 IMP cytokine-mediated signaling pathway
GO:0019855 IBA calcium channel inhibitor activity
GO:0019899 IEA enzyme binding
GO:0030018 IEA Z disc
GO:0030544 IEA Hsp70 protein binding
GO:0031000 IMP response to caffeine
GO:0031398 IEA positive regulation of protein ubiquitination
GO:0032092 IEA positive regulation of protein binding
GO:0032513 IEA negative regulation of protein phosphatase type 2B activity
GO:0032880 IEA regulation of protein localization
GO:0032925 IEA regulation of activin receptor signaling pathway
GO:0033017 IDA sarcoplasmic reticulum membrane
GO:0034713 IEA type I transforming growth factor beta receptor binding
GO:0042098 IMP T cell proliferation
GO:0042803 IDA protein homodimerization activity
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043206 IEA extracellular fibril organization
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043679 IEA axon terminus
GO:0044325 IPI ion channel binding
GO:0046332 IEA SMAD binding
GO:0048185 IEA activin binding
GO:0050776 IEA regulation of immune response
GO:0051209 IDA release of sequestered calcium ion into cytosol
GO:0051280 IBA negative regulation of release of sequestered calcium ion into cytosol
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060314 IMP regulation of ryanodine-sensitive calcium-release channel activity
GO:0060347 IMP heart trabecula formation
GO:0061077 IBA chaperone-mediated protein folding
GO:0070062 IEA extracellular vesicular exosome
GO:1902991 IEA regulation of amyloid precursor protein catabolic process
GO:1990000 IEA amyloid fibril formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000370659 FKBP1C-001 protein_coding Homo_sapiens 0 1314
ENST00000381715 FKBP1A-005 protein_coding Homo_sapiens 0 473
ENST00000381719 FKBP1A-002 protein_coding Homo_sapiens 0 544
ENST00000381724 FKBP1A-004 protein_coding Homo_sapiens 0 878
ENST00000400137 FKBP1A-001 protein_coding Homo_sapiens 0 1382
ENST00000423650 FKBP1AP3-001 processed_pseudogene Homo_sapiens 0 318
ENST00000439640 FKBP1A-201 protein_coding Homo_sapiens 0 361
ENST00000460490 FKBP1A-003 processed_transcript Homo_sapiens 0 414
ENST00000474657 FKBP1A-007 processed_transcript Homo_sapiens 0 627
ENST00000474726 FKBP1A-006 processed_transcript Homo_sapiens 0 473
ENST00000594588 AC010522.1-001 processed_pseudogene Homo_sapiens 0 351
ENST00000612074 FKBP1A-008 nonsense_mediated_decay Homo_sapiens 0 361
ENST00000614856 FKBP1A-009 protein_coding Homo_sapiens 0 326
ENST00000617804 RP11-314N13.10-002 nonsense_mediated_decay Homo_sapiens 3e-35 152
ENST00000618612 FKBP1A-202 protein_coding Homo_sapiens 0 1057
ENST00000618770 RP11-314N13.10-001 processed_transcript Homo_sapiens 2e-35 154

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