C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, Na+/K+ transporting, alpha 1 polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033161 Atp1a1 10090 - 3:101576219-101604603 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000036493 Atp1a1-001 101576219-101604603 protein_coding
  ENSMUST00000130649 Atp1a1-003 101576316-101577560 retained_intron
  ENSMUST00000136340 Atp1a1-002 101585788-101589039 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000036493
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000036493 88.747±59.98 183.444±7.53 121.806±4.16 108.220±91.39 49.057±4.39 466.402±40.94 223.646±14.83 1161.168±111.96 71.120±23.33 151.706±11.10 26.151±3.74 203.507±21.24 189.193±41.60 24.893±7.29

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002026 IMP regulation of the force of heart contraction
GO:0002028 ISS regulation of sodium ion transport
GO:0005391 IMP sodium:potassium-exchanging ATPase activity
GO:0005515 IPI protein binding
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005890 IEA sodium:potassium-exchanging ATPase complex
GO:0005901 IEA caveola
GO:0006754 IEA ATP biosynthetic process
GO:0006813 IEA potassium ion transport
GO:0006814 IEA sodium ion transport
GO:0006883 IEA cellular sodium ion homeostasis
GO:0008217 IGI regulation of blood pressure
GO:0010107 IEA potassium ion import
GO:0016020 IEA membrane
GO:0016021 ISS integral component of membrane
GO:0016311 IMP dephosphorylation
GO:0016323 IDA basolateral plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0016791 IMP phosphatase activity
GO:0019901 IEA protein kinase binding
GO:0019904 IEA protein domain specific binding
GO:0030007 IEA cellular potassium ion homeostasis
GO:0030315 IDA T-tubule
GO:0030506 IEA ankyrin binding
GO:0030955 IEA potassium ion binding
GO:0031402 IEA sodium ion binding
GO:0031947 IMP negative regulation of glucocorticoid biosynthetic process
GO:0031982 IEA vesicle
GO:0035725 IEA sodium ion transmembrane transport
GO:0036376 IEA sodium ion export from cell
GO:0042383 IDA sarcolemma
GO:0042493 IMP response to drug
GO:0043234 ISO protein complex
GO:0043531 IEA ADP binding
GO:0043548 IEA phosphatidylinositol 3-kinase binding
GO:0045121 IEA membrane raft
GO:0045822 IMP negative regulation of heart contraction
GO:0045823 IMP positive regulation of heart contraction
GO:0045989 IMP positive regulation of striated muscle contraction
GO:0051087 IEA chaperone binding
GO:0060081 IEA membrane hyperpolarization
GO:0070062 IEA extracellular vesicular exosome
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071383 IEA cellular response to steroid hormone stimulus
GO:0086004 IEA regulation of cardiac muscle cell contraction
GO:0086009 IEA membrane repolarization
GO:1903416 IEA response to glycoside
GO:1990239 IEA steroid hormone binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001870 atp1a1a.4 ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 4 protein_coding Danio_rerio
ENSDARG00000002791 atp1a1a.1 ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 1 protein_coding Danio_rerio
ENSDARG00000007739 atp1a1a.2 ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 2 protein_coding Danio_rerio
ENSDARG00000019856 atp1a1b ATPase, Na+/K+ transporting, alpha 1b polypeptide protein_coding Danio_rerio
ENSDARG00000039131 atp1a1a.3 ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 3 protein_coding Danio_rerio
ENSDARG00000040252 atp1a1a.5 ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 5 protein_coding Danio_rerio
ENSG00000163399 ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide protein_coding Homo_sapiens

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