C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor type, M
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033278 Ptprm 10090 - 17:66666848-67354459 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037974 Ptprm-201 66666848-67354459 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037974
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037974 5.856±2.37 5.799±0.42 6.268±0.91 5.809±2.16 3.799±1.82 1.587±0.76 13.754±0.88 3.684±0.86 0.430±0.14 25.705±5.65 2.704±0.21 6.026±2.52 4.263±2.91 1.010±0.53

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001937 ISS negative regulation of endothelial cell proliferation
GO:0005001 ISS transmembrane receptor protein tyrosine phosphatase activity
GO:0005737 IEA cytoplasm
GO:0005911 IEA cell-cell junction
GO:0005913 ISS cell-cell adherens junction
GO:0006470 ISS protein dephosphorylation
GO:0007156 ISS homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007165 ISS signal transduction
GO:0010596 ISS negative regulation of endothelial cell migration
GO:0010842 ISS retina layer formation
GO:0016021 IEA integral component of membrane
GO:0016525 ISS negative regulation of angiogenesis
GO:0030027 ISS lamellipodium
GO:0031175 ISS neuron projection development
GO:0031290 ISS retinal ganglion cell axon guidance
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0042493 ISS response to drug
GO:0042802 IEA identical protein binding
GO:0045296 ISS cadherin binding
GO:0045909 IMP positive regulation of vasodilation
GO:0048471 ISS perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089172 PTPRM protein tyrosine phosphatase, receptor type, M protein_coding Danio_rerio
ENSG00000173482 PTPRM protein tyrosine phosphatase, receptor type, M protein_coding Homo_sapiens

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