C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dihydropyrimidine dehydrogenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033308 Dpyd 10090 + 3:118562129-119432918 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039177 Dpyd-001 118562129-119432918 protein_coding
  ENSMUST00000126254 Dpyd-003 118562130-118799119 retained_intron
  ENSMUST00000129148 Dpyd-005 118811222-118899831 retained_intron
  ENSMUST00000149101 Dpyd-004 118562180-118674773 retained_intron
  ENSMUST00000150950 Dpyd-002 118562177-118783279 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039177ENSMUST00000126254ENSMUST00000129148ENSMUST00000149101
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039177 5.533±0.51 4.860±1.06 2.975±0.23 0.634±0.37 2.805±0.32 3.150±0.65 1.309±0.18 13.229±1.41 40.760±38.09 1.219±0.11 0.421±0.08 4.062±1.10 0.225±0.24 0.709±0.28
ENSMUST00000126254 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.019±0.00 N/A
ENSMUST00000129148 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.034±0.00 N/A
ENSMUST00000149101 N/A N/A N/A 2.555±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00005S CIL_00005S_0002 CGP 3:118562129-119783388

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004152 IEA dihydroorotate dehydrogenase activity
GO:0005737 ISS cytoplasm
GO:0005829 IDA cytosol
GO:0006145 IEA purine nucleobase catabolic process
GO:0006208 IDA pyrimidine nucleobase catabolic process
GO:0006210 IEA thymine catabolic process
GO:0006212 ISS uracil catabolic process
GO:0006214 ISS thymidine catabolic process
GO:0006222 IEA UMP biosynthetic process
GO:0017113 ISS dihydropyrimidine dehydrogenase (NADP+) activity
GO:0019483 IEA beta-alanine biosynthetic process
GO:0046872 IEA metal ion binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010267 dpydb dihydropyrimidine dehydrogenase b protein_coding Danio_rerio
ENSDARG00000071482 dpyda dihydropyrimidine dehydrogenase a protein_coding Danio_rerio
ENSDARG00000086464 DPYD (3 of 5) dihydropyrimidine dehydrogenase protein_coding Danio_rerio
ENSDARG00000086853 DPYD (4 of 5) dihydropyrimidine dehydrogenase protein_coding Danio_rerio
ENSDARG00000089675 CR855273.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000188641 DPYD dihydropyrimidine dehydrogenase protein_coding Homo_sapiens

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