C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sepiapterin reductase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033735 Spr 10090 - 6:85133678-85137766 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045986 Spr-001 85133678-85137766 protein_coding
  ENSMUST00000174286 Spr-004 85134098-85137762 protein_coding
  ENSMUST00000174769 Spr-002 85133687-85137756 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045986ENSMUST00000174286
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045986 8.927±0.51 14.597±3.01 8.787±2.26 9.105±8.12 6.755±2.74 18.335±1.25 12.318±1.75 29.113±2.77 17.005±8.31 14.101±1.52 19.539±1.49 14.092±7.49 11.252±3.20 0.922±0.26
ENSMUST00000174286 3.029±0.00 7.107±3.74 N/A 22.614±0.00 1.924±0.00 4.715±0.38 N/A N/A N/A N/A N/A 12.166±17.03 11.108±3.45 0.943±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087O CIL_00087O_0002 VISTA 6:84864955-85466474
CIL_0008RW CIL_0008RW_0002 VISTA 6:84918005-85518946
CIL_0003EH CIL_0003EH_0002 CGP 6:85133678-85204462

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004757 IEA sepiapterin reductase activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0006558 IMP L-phenylalanine metabolic process
GO:0006729 IEA tetrahydrobiopterin biosynthetic process
GO:0006809 IEA nitric oxide biosynthetic process
GO:0016265 IMP death
GO:0016491 IEA oxidoreductase activity
GO:0019889 IMP pteridine metabolic process
GO:0040014 IMP regulation of multicellular organism growth
GO:0042415 IMP norepinephrine metabolic process
GO:0042417 IMP dopamine metabolic process
GO:0042428 IMP serotonin metabolic process
GO:0046146 IMP tetrahydrobiopterin metabolic process
GO:0048667 IMP cell morphogenesis involved in neuron differentiation
GO:0050882 IMP voluntary musculoskeletal movement
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004406 spra sepiapterin reductase a protein_coding Danio_rerio
ENSDARG00000058553 sprb sepiapterin reductase b protein_coding Danio_rerio
ENSG00000116096 SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) protein_coding Homo_sapiens

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