C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peroxisome proliferative activated receptor, gamma, coactivator 1 beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033871 Ppargc1b 10090 - 18:61298136-61400431 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000063307 Ppargc1b-002 61298510-61400400 protein_coding
  ENSMUST00000075299 Ppargc1b-001 61298136-61400431 protein_coding
  ENSMUST00000142134 Ppargc1b-003 61389832-61400400 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000063307ENSMUST00000075299ENSMUST00000142134
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000063307 N/A N/A 3.867±0.00 N/A N/A N/A N/A N/A N/A N/A 0.406±0.10 0.248±0.00 N/A
ENSMUST00000075299 0.921±0.26 1.752±0.48 0.255±0.15 1.750±0.30 7.425±1.11 3.956±0.00 1.791±0.39 0.414±0.16 0.409±0.14 1.291±0.00 0.465±0.15 1.377±1.30 0.338±0.07
ENSMUST00000142134 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.712±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001104 IEA RNA polymerase II transcription cofactor activity
GO:0001503 IMP ossification
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005739 IMP mitochondrion
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006390 IMP transcription from mitochondrial promoter
GO:0007015 IMP actin filament organization
GO:0010694 IMP positive regulation of alkaline phosphatase activity
GO:0016592 IEA mediator complex
GO:0030331 IEA estrogen receptor binding
GO:0030374 ISS ligand-dependent nuclear receptor transcription coactivator activity
GO:0030520 ISS intracellular estrogen receptor signaling pathway
GO:0030546 IEA receptor activator activity
GO:0034614 IDA cellular response to reactive oxygen species
GO:0042327 IMP positive regulation of phosphorylation
GO:0045672 IMP positive regulation of osteoclast differentiation
GO:0045780 IMP positive regulation of bone resorption
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0050682 ISS AF-2 domain binding
GO:0051384 IEA response to glucocorticoid
GO:0051591 IEA response to cAMP
GO:0060346 IMP bone trabecula formation
GO:2000273 IEA positive regulation of receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056563 ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1, beta protein_coding Danio_rerio
ENSG00000155846 PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta protein_coding Homo_sapiens

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