C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peroxisome proliferator-activated receptor gamma, coactivator 1 beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000155846 PPARGC1B 9606 + 5:149730298-149855022 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309241 PPARGC1B-001 149730311-149855022 protein_coding
  ENST00000360453 PPARGC1B-005 149730298-149847562 protein_coding
  ENST00000394320 PPARGC1B-003 149730301-149847704 protein_coding
  ENST00000403750 PPARGC1B-002 149771940-149847627 protein_coding
  ENST00000434684 PPARGC1B-004 149833015-149847718 protein_coding
  ENST00000461780 PPARGC1B-006 149730303-149817746 processed_transcript
  ENST00000492495 PPARGC1B-008 149845643-149847757 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000309241ENST00000360453ENST00000394320ENST00000434684
Transcript ID Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000309241 0.518±0.16 0.426±0.00 0.790±0.00 0.902±0.41 0.234±0.01 0.544±0.40 N/A 1.226±0.00 0.299±0.30 0.185±0.02 0.168±0.12
ENST00000360453 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.184±0.00 N/A
ENST00000394320 N/A N/A N/A N/A N/A N/A 0.346±0.00 N/A N/A N/A N/A
ENST00000434684 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.385±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000851 CIL_000851_0001 VISTA 5:149141792-149745303
CIL_0001JP CIL_0001JP_0002 CGP 5:149551947-149855022
CIL_0001JR CIL_0001JR_0002 CGP 5:149730298-149944793

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001104 IDA RNA polymerase II transcription cofactor activity
GO:0001503 IEA ossification
GO:0003676 IEA nucleic acid binding
GO:0003723 NAS RNA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005739 IEA mitochondrion
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006390 IEA transcription from mitochondrial promoter
GO:0007015 IEA actin filament organization
GO:0010694 IEA positive regulation of alkaline phosphatase activity
GO:0016592 IDA mediator complex
GO:0030331 IDA estrogen receptor binding
GO:0030374 IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030520 IDA intracellular estrogen receptor signaling pathway
GO:0030546 IDA receptor activator activity
GO:0034614 IEA cellular response to reactive oxygen species
GO:0042327 IEA positive regulation of phosphorylation
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045672 IEA positive regulation of osteoclast differentiation
GO:0045780 IEA positive regulation of bone resorption
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050682 IPI AF-2 domain binding
GO:0051384 IEA response to glucocorticoid
GO:0051591 IEA response to cAMP
GO:0060346 IEA bone trabecula formation
GO:2000273 IDA positive regulation of receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056563 ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1, beta protein_coding Danio_rerio
ENSMUSG00000033871 Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta protein_coding Mus_musculus

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