C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: deiodinase, iodothyronine, type I
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034785 Dio1 10090 - 4:107291465-107307169 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000082426 Dio1-001 107291465-107307169 protein_coding
  ENSMUST00000106748 Dio1-007 107292364-107307118 protein_coding
  ENSMUST00000126291 Dio1-003 107292364-107307118 protein_coding
  ENSMUST00000129138 Dio1-006 107292334-107307124 protein_coding
  ENSMUST00000134366 Dio1-004 107292330-107307124 nonsense_mediated_decay
  ENSMUST00000145332 Dio1-008 107299817-107307066 processed_transcript
  ENSMUST00000147709 Dio1-005 107292364-107307118 nonsense_mediated_decay
  ENSMUST00000150974 Dio1-002 107292167-107307142 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000082426ENSMUST00000106748ENSMUST00000126291ENSMUST00000129138ENSMUST00000134366ENSMUST00000145332ENSMUST00000150974
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000082426 0.732±0.03 N/A 0.005±0.00 N/A 0.208±0.01 19.999±1.77 N/A 34.173±2.21 37.968±35.19 0.198±0.08 0.045±0.02 0.370±0.17 0.005±0.00 N/A
ENSMUST00000106748 1.262±0.46 0.228±0.07 N/A N/A 0.847±0.15 25.230±3.63 0.125±0.00 N/A 77.504±10.77 0.386±0.00 0.219±0.00 0.706±0.22 N/A N/A
ENSMUST00000126291 N/A 0.316±0.13 N/A N/A 0.215±0.15 N/A 0.066±0.00 N/A 0.024±0.00 0.244±0.00 N/A 0.655±0.46 N/A N/A
ENSMUST00000129138 N/A N/A N/A 0.022±0.00 0.661±0.00 N/A 0.061±0.00 N/A N/A 0.454±0.00 N/A 0.474±0.00 N/A N/A
ENSMUST00000134366 N/A N/A N/A N/A N/A 11.841±3.91 N/A N/A N/A N/A N/A 0.714±0.36 N/A N/A
ENSMUST00000145332 N/A N/A N/A 0.069±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.347±0.00
ENSMUST00000150974 N/A N/A N/A N/A 0.180±0.05 N/A N/A N/A 0.028±0.00 N/A 0.030±0.00 0.754±0.33 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004800 IDA thyroxine 5'-deiodinase activity
GO:0005783 IEA endoplasmic reticulum
GO:0008430 IDA selenium binding
GO:0016021 IEA integral component of membrane
GO:0042446 IEA hormone biosynthetic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042112 dio1 deiodinase, iodothyronine, type I protein_coding Danio_rerio
ENSG00000211452 DIO1 deiodinase, iodothyronine, type I protein_coding Homo_sapiens

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