C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: unc-13 homolog A (C. elegans)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034799 Unc13a 10090 - 8:71624417-71671757 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030170 Unc13a-001 71624417-71671757 protein_coding
  ENSMUST00000175780 Unc13a-004 71660346-71668082 retained_intron
  ENSMUST00000175909 Unc13a-008 71634623-71641397 nonsense_mediated_decay
  ENSMUST00000176127 Unc13a-007 71641460-71645953 protein_coding
  ENSMUST00000176426 Unc13a-005 71653607-71658495 protein_coding
  ENSMUST00000176777 Unc13a-003 71660341-71671741 retained_intron
  ENSMUST00000177032 Unc13a-006 71634889-71642568 retained_intron
  ENSMUST00000177517 Unc13a-002 71629054-71671736 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainColonHeartLiverOvaryTestisENSMUST00000030170ENSMUST00000177517
Transcript ID Adrenal Brain Colon Heart Liver Ovary Testis
ENSMUST00000030170 4.007±0.37 20.225±3.20 2.403±0.10 1.288±0.00 0.939±0.02 4.421±0.20 0.836±0.00
ENSMUST00000177517 N/A 24.012±16.16 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00076B CIL_00076B_0002 CGP 8:71597648-71624909
CIL_00076A CIL_00076A_0002 CGP 8:71611024-71671757

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001956 IMP positive regulation of neurotransmitter secretion
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0007269 ISS neurotransmitter secretion
GO:0007528 IGI neuromuscular junction development
GO:0010807 TAS regulation of synaptic vesicle priming
GO:0016081 IGI synaptic vesicle docking involved in exocytosis
GO:0016188 IMP synaptic vesicle maturation
GO:0017075 ISS syntaxin-1 binding
GO:0019992 IDA diacylglycerol binding
GO:0030054 IEA cell junction
GO:0030424 IDA axon
GO:0031594 IDA neuromuscular junction
GO:0035249 IGI synaptic transmission, glutamatergic
GO:0035556 IEA intracellular signal transduction
GO:0042734 ISS presynaptic membrane
GO:0043005 ISS neuron projection
GO:0045202 IDA synapse
GO:0046872 IEA metal ion binding
GO:0047485 ISS protein N-terminus binding
GO:0048172 IMP regulation of short-term neuronal synaptic plasticity
GO:0050435 IMP beta-amyloid metabolic process
GO:0060384 IGI innervation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061829 UNC13A (1 of 5) unc-13 homolog A (C. elegans) protein_coding Danio_rerio
ENSDARG00000091647 UNC13A (5 of 5) unc-13 homolog A (C. elegans) protein_coding Danio_rerio
ENSG00000130477 UNC13A unc-13 homolog A (C. elegans) protein_coding Homo_sapiens

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