C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal peptide peptidase like 2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035206 Sppl2b 10090 + 10:80855275-80868705 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035597 Sppl2b-201 80855275-80868705 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035597
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035597 19.073±3.21 35.516±1.90 12.351±0.74 23.936±13.97 23.909±10.26 33.251±4.72 9.859±0.61 16.983±3.74 25.301±21.49 21.155±2.58 3.351±1.21 31.748±15.10 8.137±1.65 38.960±17.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001IB CIL_0001IB_0002 CGP 10:80852825-80868705
CIL_0003DX CIL_0003DX_0002 CGP 10:80855275-80899441

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005765 ISS lysosomal membrane
GO:0005886 ISS plasma membrane
GO:0006509 ISS membrane protein ectodomain proteolysis
GO:0010008 ISS endosome membrane
GO:0030660 ISS Golgi-associated vesicle membrane
GO:0031293 ISS membrane protein intracellular domain proteolysis
GO:0042500 ISS aspartic endopeptidase activity, intramembrane cleaving
GO:0042803 ISS protein homodimerization activity
GO:0050776 ISS regulation of immune response
GO:0071458 ISS integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 ISS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030448 sppl2 signal peptide peptidase-like 2 protein_coding Danio_rerio
ENSG00000005206 SPPL2B signal peptide peptidase like 2B protein_coding Homo_sapiens

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